Albalon (Naphazoline hydrochloride)

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Albalon Information

Brand Name	Albalon
Product Code	11980-154
Company Name	Allergan Inc.
Dosage From	SOLUTION
Strength	1 mg
Inactive Ingredient	citric acid, monohydrate,edetate disodium,polyvinyl alcohol,water,sodium chloride,sodium citrate, dihydrate,benzalkonium chloride,sodium hydroxide,

Albalon (Naphazoline hydrochloride)

Albalon (Naphazoline hydrochloride) Description

Naphazoline hydrochloride, an ocular vasoconstrictor, is an imidazoline derivative sympathomimetic amine. It occurs as a white, odorless crystalline powder having a bitter taste and is freely soluble in water and in alcohol. The active ingredient is represented by the structural formula:

Albalon (Naphazoline hydrochloride) Clinical Pharmacology

Naphazoline constricts the vascular system of the conjunctiva. It is presumed that this effect is due to direct stimulation action of the drug upon the alpha-adrenergic receptors in the arterioles of the conjunctiva, resulting in decreased conjunctival congestion. Naphazoline belongs to the imidazoline class of sympathomimetics.

Albalon (Naphazoline hydrochloride) Indications And Usage

Albalon (Naphazoline hydrochloride) (naphazoline hydrochloride ophthalmic solution, USP) 0.1% is indicated for use as a topical ocular vasoconstrictor.

Albalon (Naphazoline hydrochloride) Contraindications

Albalon (Naphazoline hydrochloride) ophthalmic solution is contraindicated in the presence of an anatomically narrow angle or in narrow-angle glaucoma or in persons who have shown hypersensitivity to any component of this preparation.

Albalon (Naphazoline hydrochloride) Warnings

Patients under therapy with MAO inhibitors may experience a severe hypertensive crisis if given a sympathomimetic drug. Use in children, especially infants, may result in CNS depression leading to coma and marked reduction in body temperature.

Albalon (Naphazoline hydrochloride) Precautions

Patients should be advised to discontinue the drug and consult a physician if relief is not obtained within 48 hours of therapy, if irritation, blurring or redness persists or increases, or if symptoms of systemic absorption occur, i.e., dizziness, headache, nausea, decrease in body temperature, or drowsiness.

To prevent contaminating the dropper tip and solution, do not touch the eyelids or the surrounding area with the dropper tip of the bottle. If solution changes color or becomes cloudy, do not use.

Albalon (Naphazoline hydrochloride) Adverse Reactions

Ocular:

Systemic:

Albalon (Naphazoline hydrochloride) Dosage And Administration

Instill one or two drops in the conjunctival sac(s) every three to four hours as needed.

Albalon (Naphazoline hydrochloride) How Supplied

Albalon (Naphazoline hydrochloride) (naphazoline hydrochloride ophthalmic solution, USP) 0.1% is supplied sterile in opaque white LDPE plastic bottles with dropper tips and white high impact polystyrene (HIPS) caps as follows:

15 mL in 15 mL bottle – 11980-154-15

4701X

71583US10M