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Zymar Price Comparison

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Zymar Prices from BuyLow Drugs

Zymar 0.3 %

15
Brand

$51.00

viewdetail

$ 3.40

Go To STORE
35.46%
When you buy 1 container of Zymar 0.3 % for $51.00 at BuyLow Drugs compared to the max price for 15 of $79.02.
1 container (15): Zymar 0.3 %
$51.00
Regular Shipping:
$0.00
Total:
$51
Go To Store

Zymar Prices from Online Canadian Pharmacy

Zymar 0.30%

15 Ml
Brand

$52.16

viewdetail

$ 3.48

Go To STORE
33.99%
When you buy 1 container of Zymar 0.30% for $52.16 at Online Canadian Pharmacy compared to the max price for 15 Ml of $79.02.
1 container (15 Ml): Zymar 0.30%
$52.16
Regular Shipping:
$0.00
Total:
$52.16
Go To Store

Zymar Prices from MapleLeafMeds

Zymar 0.30%

15 Ml
Brand

$52.50

viewdetail

$ 3.50

Go To STORE
33.56%
When you buy 1 container of Zymar 0.30% for $52.50 at MapleLeafMeds compared to the max price for 15 Ml of $79.02.
MapleLeafMeds Pharmacy is certified by
1 container (15 Ml): Zymar 0.30%
$52.50
Regular Shipping:
$9.95
Total:
$62.45
Go To Store

Zymar Prices from DoctorSolve

Zymar 0.30%

15 Ml
Brand

$52.50

viewdetail

$ 3.50

Go To STORE
33.56%
When you buy 1 container of Zymar 0.30% for $52.50 at DoctorSolve compared to the max price for 15 Ml of $79.02.
DoctorSolve Pharmacy is certified by
1 container (15 Ml): Zymar 0.30%
$52.50
Regular Shipping:
$9.95
Coupon Discount
$15.6125
Total:
$46.8375
Go To Store

Zymar Prices from PrescriptionPoint

Zymar 0.30%

15 Ml
Brand

$52.50

viewdetail

$ 3.50

Go To STORE
33.56%
When you buy 1 container of Zymar 0.30% for $52.50 at PrescriptionPoint compared to the max price for 15 Ml of $79.02.
PrescriptionPoint Pharmacy is certified by
1 container (15 Ml): Zymar 0.30%
$52.50
Regular Shipping:
$9.95
Total:
$62.45
Go To Store

Zymar Prices from Online Pharmacies Canada

Zymar 0.30%

15 Ml
Brand

$60.57

viewdetail

$ 4.04

Go To STORE
23.35%
When you buy 1 container of Zymar 0.30% for $60.57 at Online Pharmacies Canada compared to the max price for 15 Ml of $79.02.
Online Pharmacies Canada Pharmacy is certified by
1 container (15 Ml): Zymar 0.30%
$60.57
Regular Shipping:
$9.95
Total:
$70.52
Go To Store

Zymar Prices from Quality Prescription Drugs

Zymar 0.30%

15 Ml
Brand

$60.72

viewdetail

$ 4.05

Go To STORE
23.16%
When you buy 1 container of Zymar 0.30% for $60.72 at Quality Prescription Drugs compared to the max price for 15 Ml of $79.02.
Quality Prescription Drugs Pharmacy is certified by
1 container (15 Ml): Zymar 0.30%
$60.72
Regular Shipping:
$9.00
Total:
$69.72
Go To Store

Zymar Prices from Pharma Passport

Zymar 0.30%

15 Ml
Brand

$60.87

viewdetail

$ 4.06

Go To STORE
22.97%
When you buy 1 container of Zymar 0.30% for $60.87 at Pharma Passport compared to the max price for 15 Ml of $79.02.
1 container (15 Ml): Zymar 0.30%
$60.87
Regular Shipping:
$9.95
Total:
$70.82
Go To Store

Zymar Prices from JanDrugs

Zymar 0.3%

15 ml
Brand

$79.02

viewdetail

$ 5.27

Go To STORE
0.00%
When you buy 1 container of Zymar 0.3% for $79.02 at JanDrugs compared to the max price for 15 ml of $79.02.
JanDrugs Pharmacy is certified by
1 container (15 ml): Zymar 0.3%
$79.02
Regular Shipping:
$0.00
Coupon Discount
$7.902
Total:
$71.118
Go To Store

Zymar Prices from Canada Drugs

Zymar 0.3%

15 ml
Brand

$79.02

viewdetail

$ 5.27

Go To STORE
0.00%
When you buy 1 container of Zymar 0.3% for $79.02 at Canada Drugs compared to the max price for 15 ml of $79.02.
Canada Drugs Pharmacy is certified by
1 container (15 ml): Zymar 0.3%
$79.02
Regular Shipping:
$0.00
Coupon Discount
$19.755
Total:
$59.265
Go To Store

Zymar Prices from BuyLow Drugs

Zymar drops 0.3%

5
Brand

$27.00

viewdetail

$ 5.40

Go To STORE
23.60%
When you buy 1 container of Zymar drops 0.3% for $27.00 at BuyLow Drugs compared to the max price for 5 of $35.34.
1 container (5): Zymar drops 0.3%
$27.00
Regular Shipping:
$0.00
Total:
$27
Go To Store

Zymar Prices from JanDrugs

Zymar 0.3%

5 ml
Brand

$35.34

viewdetail

$ 7.07

Go To STORE
0.00%
When you buy 1 container of Zymar 0.3% for $35.34 at JanDrugs compared to the max price for 5 ml of $35.34.
JanDrugs Pharmacy is certified by
1 container (5 ml): Zymar 0.3%
$35.34
Regular Shipping:
$0.00
Coupon Discount
$3.534
Total:
$31.806
Go To Store

Zymar Prices from Canada Drugs

Zymar 0.3%

5 ml
Brand

$35.34

viewdetail

$ 7.07

Go To STORE
0.00%
When you buy 1 container of Zymar 0.3% for $35.34 at Canada Drugs compared to the max price for 5 ml of $35.34.
Canada Drugs Pharmacy is certified by
1 container (5 ml): Zymar 0.3%
$35.34
Regular Shipping:
$0.00
Coupon Discount
$8.835
Total:
$26.505
Go To Store

Zymar Prices from CanadianPharmacyKing

Zymar 0.3 %/5 ml

3
Brand

$79.00

viewdetail

$ 26.33

Go To STORE
0.00%
When you buy 1 container of Zymar 0.3 %/5 ml for $79.00 at CanadianPharmacyKing compared to the max price for 3 of $79.00.
CanadianPharmacyKing Pharmacy is certified by
1 container (3): Zymar 0.3 %/5 ml
$79.00
Regular Shipping:
$10.00
Total:
$89
Go To Store

Zymar Prices from CanadianPharmacyKing

Zymar 0.3 %/5 ml

2
Brand

$57.00

viewdetail

$ 28.50

Go To STORE
0.00%
When you buy 1 container of Zymar 0.3 %/5 ml for $57.00 at CanadianPharmacyKing compared to the max price for 2 of $57.00.
CanadianPharmacyKing Pharmacy is certified by
1 container (2): Zymar 0.3 %/5 ml
$57.00
Regular Shipping:
$10.00
Total:
$67
Go To Store

Zymar Prices from Canadian Pharmacy Meds

Zymar Opthalmic Solution 5ml 0.003

1
Brand

$31.00

viewdetail

$ 31.00

Go To STORE
59.21%
When you buy 1 container of Zymar Opthalmic Solution 5ml 0.003 for $31.00 at Canadian Pharmacy Meds compared to the max price for 1 of $76.00.
Canadian Pharmacy Meds Pharmacy is certified by
1 container (1): Zymar Opthalmic Solution 5ml 0.003
$31.00
Regular Shipping:
$10.00
Coupon Discount
$4.1
Total:
$36.9
Go To Store

Zymar Prices from CanadianPharmacyKing

Zymar 0.3 %/5 ml

1
Brand

$40.00

viewdetail

$ 40.00

Go To STORE
47.37%
When you buy 1 container of Zymar 0.3 %/5 ml for $40.00 at CanadianPharmacyKing compared to the max price for 1 of $76.00.
CanadianPharmacyKing Pharmacy is certified by
1 container (1): Zymar 0.3 %/5 ml
$40.00
Regular Shipping:
$10.00
Total:
$50
Go To Store

Zymar Prices from Canadian Pharmacy Meds

Zymar Opthalmic Solution 15ml 0.003

1
Brand

$76.00

viewdetail

$ 76.00

Go To STORE
0.00%
When you buy 1 container of Zymar Opthalmic Solution 15ml 0.003 for $76.00 at Canadian Pharmacy Meds compared to the max price for 1 of $76.00.
Canadian Pharmacy Meds Pharmacy is certified by
1 container (1): Zymar Opthalmic Solution 15ml 0.003
$76.00
Regular Shipping:
$10.00
Coupon Discount
$8.6
Total:
$77.4
Go To Store

Zymar Information

Product Code
0023-9218
Company Name
Allergan, Inc.
Dosage From
SOLUTION/ DROPS
Strength
3 mg
Active Ingredient
gatifloxacin

Zymar () Description

Zymar () Clinical Pharmacology

Pharmacokinetics:

Microbiology:
Topoisomerase IV is an enzyme known to play a key role in the partitioning of the chromosomal DNA during bacterial cell division.

The mechanism of action of fluoroquinolones including gatifloxacin is different from that of aminoglycoside, macrolide, and tetracycline antibiotics. Therefore, gatifloxacin may be active against pathogens that are resistant to these antibiotics and these antibiotics may be active against pathogens that are resistant to gatifloxacin. There is no cross-resistance between gatifloxacin and the aforementioned classes of antibiotics. Cross resistance has been observed between systemic gatifloxacin and some other fluoroquinolones.

Resistance to gatifloxacin develops via multiple-step mutations. Resistance to gatifloxacin occurs at a general frequency of between 1 x 10 to 10.

Gatifloxacin has been shown to be active against most strains of the following organisms both and clinically, in conjunctival infections as described in the section.

*
The following data are available, The safety and effectiveness of in treating ophthalmic infections due to the following organisms have not been established in adequate and well-controlled clinical trials.

The following organisms are considered susceptible when evaluated using systemic breakpoints. However, a correlation between the systemic breakpoint and ophthalmological efficacy has not been established.

The following list of organisms is provided as guidance only in assessing the potential treatment of conjunctival infections. Gatifloxacin exhibits minimal inhibitory concentrations (MICs) of 2 μg/mL or less (systemic susceptible breakpoint) against most (≥ 90%) strains of the following ocular pathogens.

Clinical Studies:
Zymar ()

Zymar () Contraindications

Zymar ()

Zymar () Warnings

NOT FOR INJECTION.

In patients receiving systemic quinolones, including gatifloxacin, serious and occasionally fatal hypersensitivity (anaphylactic) reactions, some following the first dose, have been reported. Some reactions were accompanied by cardiovascular collapse, loss of consciousness, angioedema (including laryngeal, pharyngeal or facial edema), airway obstruction, dyspnea, urticaria, and itching. If an allergic reaction to gatifloxacin occurs, discontinue the drug. Serious acute hypersensitivity reactions may require immediate emergency treatment. Oxygen and airway management should be administered as clinically indicated.

Zymar () Precautions

General:
Patients should be advised not to wear contact lenses if they have signs and symptoms of bacterial conjunctivitis.

Information for Patients:
Systemic quinolones, including gatifloxacin, have been associated with hypersensitivity reactions, even following a single dose. Discontinue use immediately and contact your physician at the first sign of a rash or allergic reaction.

Drug Interactions:
Zymar ()
There was no increase in neoplasms among B6C3F1 mice given gatifloxacin in the diet for 18 months at doses averaging 81 mg/kg/day in males and 90 mg/kg/day in females. These doses are approximately 2000-fold higher than the maximum recommended ophthalmic dose of 0.04 mg/kg/day in a 50 kg human.

There was no increase in neoplasms among Fischer 344 rats given gatifloxacin in the diet for 2 years at doses averaging 47 mg/kg/day in males and 139 mg/kg/day in females (1000 and 3000-fold higher, respectively, than the maximum recommended ophthalmic dose). A statistically significant increase in the incidence of large granular lymphocyte (LGL) leukemia was seen in males treated with a high dose of approximately 2000-fold higher than the maximum recommended ophthalmic dose. Fischer 344 rats have a high spontaneous background rate of LGL leukemia and the incidence in high-dose males only slightly exceeded the historical control range established for this strain.

In genetic toxicity tests, gatifloxacin was positive in 1 of 5 strains used in bacterial reverse mutation assays; Salmonella strain TA102. Gatifloxacin was positive in mammalian cell mutation and chromosome aberration assays. Gatifloxacin was positive in unscheduled DNA synthesis in rat hepatocytes but not human leukocytes. Gatifloxacin was negative in micronucleus tests in mice, cytogenetics test in rats, and DNA repair test in rats. The findings may be due to the inhibitory effects of high concentrations on eukaryotic type II DNA topoisomerase.

There were no adverse effects on fertility or reproduction in rats given gatifloxacin orally at doses up to 200 mg/kg/day (approximately 4500-fold higher than the maximum recommended ophthalmic dose for ).

There were no teratogenic effects observed in rats or rabbits following oral gatifloxacin doses up to 50 mg/kg/day (approximately 1000-fold higher than the maximum recommended ophthalmic dose). However, skeletal/craniofacial malformations or delayed ossification, atrial enlargement, and reduced fetal weight were observed in fetuses from rats given ≥150 mg/kg/day (approximately 3000-fold higher than the maximum recommended ophthalmic dose). In a perinatal/postnatal study, increased late post-implantation loss and neonatal/perinatal mortalities were observed at 200 mg/kg/day (approximately 4500 times the maximum recommended ophthalmic dose).

Because there are no adequate and well-controlled studies in pregnant women, solution should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Nursing Mothers:

Pediatric Use:

Geriatric Use:

Zymar () Dosage And Administration

The recommended dosage regimen for the treatment of bacterial conjunctivitis is:

Days 1 and 2: Instill one drop every two hours in the affected eye(s) while awake, up to 8 times daily.

Days 3 through 7: Instill one drop up to four times daily while awake.

Zymar () How Supplied

              5 mL in 10 mL bottle - NDC 0023-9218-05

Zymar () Animal Pharmacology

Quinolone antibacterials have been shown to cause bone or cartilage changes in immature animals. There was no evidence of bone cartilage changes following ocular administration of gatifloxacin in rabbits or dogs.

© 2010 Allergan, Inc. Irvine, CA 92612, U.S.A. marks owned by Allergan, Inc.Licensed from Kyorin Pharmaceuticals Co., Ltd. U.S. Patents 5,880,283 and 6,333,045 Made in the U.S.A.

71706US13B

Zymar ()

Zymar ()

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