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Vexol Price Comparison

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Vexol Prices from JanDrugs

Vexol 1%

15 ml
Brand

$85.05

viewdetail

$ 5.67

Go To STORE
0.00%
When you buy 1 container of Vexol 1% for $85.05 at JanDrugs compared to the max price for 15 ml of $85.05.
JanDrugs Pharmacy is certified by
1 container (15 ml): Vexol 1%
$85.05
Regular Shipping:
$0.00
Coupon Discount
$8.505
Total:
$76.545
Go To Store

Vexol Prices from Canada Drugs

Vexol 1%

15 ml
Brand

$85.05

viewdetail

$ 5.67

Go To STORE
0.00%
When you buy 1 container of Vexol 1% for $85.05 at Canada Drugs compared to the max price for 15 ml of $85.05.
Canada Drugs Pharmacy is certified by
1 container (15 ml): Vexol 1%
$85.05
Regular Shipping:
$0.00
Coupon Discount
$21.2625
Total:
$63.7875
Go To Store

Vexol Prices from Online Pharmacies Canada

Vexol Eyedrops 1%

5 Ml
Brand

$33.17

viewdetail

$ 6.63

Go To STORE
26.29%
When you buy 1 container of Vexol Eyedrops 1% for $33.17 at Online Pharmacies Canada compared to the max price for 5 Ml of $45.00.
Online Pharmacies Canada Pharmacy is certified by
1 container (5 Ml): Vexol Eyedrops 1%
$33.17
Regular Shipping:
$9.95
Total:
$43.12
Go To Store

Vexol Prices from Online Pharmacies Canada

Vexol 1%

5 Ml
Brand

$33.17

viewdetail

$ 6.63

Go To STORE
26.29%
When you buy 1 container of Vexol 1% for $33.17 at Online Pharmacies Canada compared to the max price for 5 Ml of $45.00.
Online Pharmacies Canada Pharmacy is certified by
1 container (5 Ml): Vexol 1%
$33.17
Regular Shipping:
$9.95
Total:
$43.12
Go To Store

Vexol Prices from Quality Prescription Drugs

Vexol Eyedrops 1%

5 Ml
Brand

$33.25

viewdetail

$ 6.65

Go To STORE
26.11%
When you buy 1 container of Vexol Eyedrops 1% for $33.25 at Quality Prescription Drugs compared to the max price for 5 Ml of $45.00.
Quality Prescription Drugs Pharmacy is certified by
1 container (5 Ml): Vexol Eyedrops 1%
$33.25
Regular Shipping:
$9.00
Total:
$42.25
Go To Store

Vexol Prices from Quality Prescription Drugs

Vexol 1%

5 Ml
Brand

$33.25

viewdetail

$ 6.65

Go To STORE
26.11%
When you buy 1 container of Vexol 1% for $33.25 at Quality Prescription Drugs compared to the max price for 5 Ml of $45.00.
Quality Prescription Drugs Pharmacy is certified by
1 container (5 Ml): Vexol 1%
$33.25
Regular Shipping:
$9.00
Total:
$42.25
Go To Store

Vexol Prices from Pharma Passport

Vexol Eyedrops 1%

5 Ml
Brand

$33.33

viewdetail

$ 6.67

Go To STORE
25.93%
When you buy 1 container of Vexol Eyedrops 1% for $33.33 at Pharma Passport compared to the max price for 5 Ml of $45.00.
1 container (5 Ml): Vexol Eyedrops 1%
$33.33
Regular Shipping:
$9.95
Total:
$43.28
Go To Store

Vexol Prices from Pharma Passport

Vexol 1%

5 Ml
Brand

$33.33

viewdetail

$ 6.67

Go To STORE
25.93%
When you buy 1 container of Vexol 1% for $33.33 at Pharma Passport compared to the max price for 5 Ml of $45.00.
1 container (5 Ml): Vexol 1%
$33.33
Regular Shipping:
$9.95
Total:
$43.28
Go To Store

Vexol Prices from Online Canadian Pharmacy

Vexol Eyedrops 1%

5 Ml
Brand

$35.32

viewdetail

$ 7.06

Go To STORE
21.51%
When you buy 1 container of Vexol Eyedrops 1% for $35.32 at Online Canadian Pharmacy compared to the max price for 5 Ml of $45.00.
1 container (5 Ml): Vexol Eyedrops 1%
$35.32
Regular Shipping:
$0.00
Total:
$35.32
Go To Store

Vexol Prices from JanDrugs

Vexol 1%

5 ml
Brand

$37.35

viewdetail

$ 7.47

Go To STORE
17.00%
When you buy 1 container of Vexol 1% for $37.35 at JanDrugs compared to the max price for 5 ml of $45.00.
JanDrugs Pharmacy is certified by
1 container (5 ml): Vexol 1%
$37.35
Regular Shipping:
$0.00
Coupon Discount
$3.735
Total:
$33.615
Go To Store

Vexol Prices from Canada Drugs

Vexol 1%

5 ml
Brand

$37.35

viewdetail

$ 7.47

Go To STORE
17.00%
When you buy 1 container of Vexol 1% for $37.35 at Canada Drugs compared to the max price for 5 ml of $45.00.
Canada Drugs Pharmacy is certified by
1 container (5 ml): Vexol 1%
$37.35
Regular Shipping:
$0.00
Coupon Discount
$9.3375
Total:
$28.0125
Go To Store

Vexol Prices from PrescriptionPoint

Vexol 1%

5 Ml
Brand

$45.00

viewdetail

$ 9.00

Go To STORE
0.00%
When you buy 1 container of Vexol 1% for $45.00 at PrescriptionPoint compared to the max price for 5 Ml of $45.00.
PrescriptionPoint Pharmacy is certified by
1 container (5 Ml): Vexol 1%
$45.00
Regular Shipping:
$9.95
Total:
$54.95
Go To Store

Vexol Prices from DoctorSolve

Vexol Eyedrops 1%

5 Ml
Brand

$45.00

viewdetail

$ 9.00

Go To STORE
0.00%
When you buy 1 container of Vexol Eyedrops 1% for $45.00 at DoctorSolve compared to the max price for 5 Ml of $45.00.
DoctorSolve Pharmacy is certified by
1 container (5 Ml): Vexol Eyedrops 1%
$45.00
Regular Shipping:
$9.95
Coupon Discount
$13.7375
Total:
$41.2125
Go To Store

Vexol Prices from MapleLeafMeds

Vexol Eyedrops 1%

5 Ml
Brand

$45.00

viewdetail

$ 9.00

Go To STORE
0.00%
When you buy 1 container of Vexol Eyedrops 1% for $45.00 at MapleLeafMeds compared to the max price for 5 Ml of $45.00.
MapleLeafMeds Pharmacy is certified by
1 container (5 Ml): Vexol Eyedrops 1%
$45.00
Regular Shipping:
$9.95
Total:
$54.95
Go To Store

Vexol Prices from MapleLeafMeds

Vexol 1%

5 Ml
Brand

$45.00

viewdetail

$ 9.00

Go To STORE
0.00%
When you buy 1 container of Vexol 1% for $45.00 at MapleLeafMeds compared to the max price for 5 Ml of $45.00.
MapleLeafMeds Pharmacy is certified by
1 container (5 Ml): Vexol 1%
$45.00
Regular Shipping:
$9.95
Total:
$54.95
Go To Store

Vexol Prices from DoctorSolve

Vexol 1%

5 Ml
Brand

$45.00

viewdetail

$ 9.00

Go To STORE
0.00%
When you buy 1 container of Vexol 1% for $45.00 at DoctorSolve compared to the max price for 5 Ml of $45.00.
DoctorSolve Pharmacy is certified by
1 container (5 Ml): Vexol 1%
$45.00
Regular Shipping:
$9.95
Coupon Discount
$13.7375
Total:
$41.2125
Go To Store

Vexol Prices from PrescriptionPoint

Vexol Eyedrops 1%

5 Ml
Brand

$45.00

viewdetail

$ 9.00

Go To STORE
0.00%
When you buy 1 container of Vexol Eyedrops 1% for $45.00 at PrescriptionPoint compared to the max price for 5 Ml of $45.00.
PrescriptionPoint Pharmacy is certified by
1 container (5 Ml): Vexol Eyedrops 1%
$45.00
Regular Shipping:
$9.95
Total:
$54.95
Go To Store

Vexol Prices from CanadianPharmacyKing

Vexol 1 %/5 ml

3
Brand

$77.00

viewdetail

$ 25.67

Go To STORE
0.00%
When you buy 1 container of Vexol 1 %/5 ml for $77.00 at CanadianPharmacyKing compared to the max price for 3 of $77.00.
CanadianPharmacyKing Pharmacy is certified by
1 container (3): Vexol 1 %/5 ml
$77.00
Regular Shipping:
$10.00
Total:
$87
Go To Store

Vexol Prices from CanadianPharmacyKing

Vexol 1 %/5 ml

2
Brand

$60.00

viewdetail

$ 30.00

Go To STORE
0.00%
When you buy 1 container of Vexol 1 %/5 ml for $60.00 at CanadianPharmacyKing compared to the max price for 2 of $60.00.
CanadianPharmacyKing Pharmacy is certified by
1 container (2): Vexol 1 %/5 ml
$60.00
Regular Shipping:
$10.00
Total:
$70
Go To Store

Vexol Prices from Canadian Pharmacy Meds

Vexol Eyedrops 5ml 0.01

1
Brand

$46.00

viewdetail

$ 46.00

Go To STORE
0.00%
When you buy 1 container of Vexol Eyedrops 5ml 0.01 for $46.00 at Canadian Pharmacy Meds compared to the max price for 1 of $46.00.
Canadian Pharmacy Meds Pharmacy is certified by
1 container (1): Vexol Eyedrops 5ml 0.01
$46.00
Regular Shipping:
$10.00
Coupon Discount
$5.6
Total:
$50.4
Go To Store

Vexol Information

Product Code
0065-0627
Company Name
Alcon Laboratories, Inc
Dosage From
SUSPENSION
Strength
10 mg
Active Ingredient
RIMEXOLONE

Vexol (Rimexolone) Description

Vexol (Rimexolone) ® 1% Ophthalmic Suspension is a sterile, multi-dose topical ophthalmic suspension containing the corticosteroid, rimexolone. Rimexolone is a white, water-insoluble powder with an empirical formula of CHO and a molecular weight of 370.53. Its chemical name is 11β-Hydroxy-16α,17α-dimethyl-17-propio nylandrosta-1,4-diene-3-one.The chemical structure of rimexolone is presented below:

The pH of the suspension is 6.0 to 8.0 and the tonicity is 260 to 320 mOsmol/kg.

Vexol (Rimexolone) Clinical Pharmacology

Corticosteroids suppress the inflammatory response to a variety of inciting agents of a mechanical, chemical, or immunological nature. They inhibit edema, cellular infiltration, capillary dilatation, fibroblastic proliferation, deposition of collagen and scar formation associated with inflammation. Placebo-controlled clinical studies demonstrated that Vexol (Rimexolone) ® 1% Ophthalmic Suspension is efficacious for the treatment of anterior chamber inflammation following cataract surgery.

In two controlled clinical trials, Vexol (Rimexolone) ® 1% Ophthalmic Suspension demonstrated clinical equivalence to 1% prednisolone acetate in reducing uveitic inflammation. In a controlled 6-week study of steroid responsive subjects, the time to raise intraocular pressure was similar for Vexol (Rimexolone) ® 1% Ophthalmic Suspension and 0.1% fluorometholone given four times daily.

As with other topically administered ophthalmic drugs, Vexol (Rimexolone) ® 1% (rimexolone ophthalmic suspension) is absorbed systemically. Studies in normal volunteers dosed bilaterally once every hour during waking hours for one week have demonstrated serum concentrations ranging from less than 80 pg/mL to 470 pg/mL. The mean serum concentrations were approximately 130 pg/mL. Serum concentrations were at or near steady state after 5 to 7 hourly doses. After decreasing the dosing frequency to once every two hours while awake during the second week of administration, mean serum concentrations were approximately 100 pg/mL.

The serum half-life of rimexolone could not be reliably estimated due to the large number of samples below the quantitation limit of the assay (80 pg/mL). However, based on the time required to reach steady-state, the half-life appears to be short (1 - 2 hours).

Based upon and preclinical metabolism studies, and on results with human liver preparations, rimexolone undergoes extensive metabolism. Following IV administration of radio-labeled rimexolone to rats, greater than 80% of the dose is excreted via the feces as rimexolone and metabolites. Metabolites have been shown to be less active than parent drug, or inactive in human glucocorticoid receptor binding assays.

Vexol (Rimexolone) Indications And Usage

Vexol (Rimexolone) ® 1% (rimexolone ophthalmic suspension) is indicated for the treatment of postoperative inflammation following ocular surgery and in the treatment of anterior uveitis.

Vexol (Rimexolone) Contraindications

Vexol (Rimexolone) ® 1% (rimexolone ophthalmic suspension) is contraindicated in epithelial herpes simplex keratitis (dendritic keratitis), vaccinia, varicella, and most other viral diseases of the cornea and conjunctiva; mycobacterial infection of the eye; fungal diseases of the eye; acute purulent untreated infections which, like other diseases caused by microorganisms, may be masked or enhanced by the presence of the steroid; and in those persons with hypersensitivity to any component of the formulation.

Vexol (Rimexolone) Warnings

FOR TOPICAL OPHTHALMIC USE ONLY. Not for injection. Use in the treatment of herpes simplex infection requires great caution and frequent slit-lamp examinations. Prolonged use may result in ocular hypertension/glaucoma, damage to the optic nerve, defects in visual acuity and visual fields, and posterior subcapsular cataract formation.

Prolonged use may also result in secondary ocular infections due to suppression of host response.

Acute purulent infections of the eye may be masked or exacerbated by the presence of corticosteroid medication. In those diseases causing thinning of the cornea or sclera, perforation has been known to occur with topical steroids. It is advisable that the intraocular pressure be checked frequently.

Vexol (Rimexolone) Precautions

Fungal infections of the cornea are particularly prone to develop coincidentally with long-term local steroid application. Fungal invasion must be considered in any persistent corneal ulceration where a steroid has been or is in use.

For ophthalmic use only. The initial prescription and renewal of the medication order beyond 14 days should be made by a physician only after examination of the patient with the aid of magnification, such as slit lamp biomicroscopy and where appropriate, fluorescein staining. If signs and symptoms fail to improve after two days, the patient should be reevaluated.

If this product is used for 10 days or longer, intraocular pressure should be monitored even though it may be difficult in children and uncooperative patients (see ).

Rimexolone has been shown to be non-mutagenic in a battery of and mutagenicity assays.

Fertility and reproductive capability were not impaired in a study in rats with plasma levels (42 ng/mL) approximately 200 times those obtained in clinical studies after topical administration (

Vexol (Rimexolone) Adverse Reactions

Reactions associated with ophthalmic steroids include elevated intraocular pressure, which may be associated with optic nerve damage, visual acuity and field defects, posterior subcapsular cataract formation, secondary ocular infection from pathogens including herpes simplex, and perforation of the globe where there is thinning of the cornea or sclera.

Ocular adverse reactions occurring in 1 - 5% of patients in clinical studies of Vexol (Rimexolone) ® 1% (rimexolone ophthalmic suspension) included blurred vision, discharge, discomfort, ocular pain, increased intraocular pressure, foreign body sensation, hyperemia and pruritus.

Other ocular adverse reactions occurring in less than 1% of patients included sticky sensation, increased fibrin, dry eye, conjunctival edema, corneal staining, keratitis, tearing, photophobia, edema, irritation, corneal ulcer, browache, lid margin crusting, corneal edema, infiltrate, and corneal erosion.

Non-ocular adverse reactions occurred in less than 2% of patients. These included headache, hypotension, rhinitis, pharyngitis, and taste perversion.

Vexol (Rimexolone) Dosage And Administration

Apply one - two drops of Vexol (Rimexolone) ® 1% Ophthalmic Suspension into the conjunctival sac of the affected eye four times daily beginning 24 hours after surgery and continuing throughout the first 2 weeks of the postoperative period.

Apply one - two drops of Vexol (Rimexolone) ® 1% Ophthalmic Suspension into the conjunctival sac of the affected eye every hour during waking hours for the first week, one drop every two hours during waking hours of the second week, and then taper until uveitis is resolved.

Vexol (Rimexolone) How Supplied

5 mL and 10 mL in plastic DROP-TAINER® dispensers. Vexol (Rimexolone) ® 1% Ophthalmic Suspension is supplied in natural (clear) low density polyethylene (LDPE) bottles, with a natural LDPE dispensing plug and pink polypropylene closures. Fill volumes are 5 mL in an 8 mL bottle and 10 mL in a 10 mL bottle.

5 mL:    NDC 0065-0627-07

10 mL:  NDC 0065-0627-03

DO NOT FREEZE.

Vexol (Rimexolone) ® is a registered trademark of N.V. Organon.

Vexol (Rimexolone)

Vexol (Rimexolone) Principal Display Panel

(rimexolone

ophthalmic

suspension)

Sterile

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