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Phoslo Price Comparison

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Phoslo Prices from Canada Drugs

Phoslo 667mg

200 capsule
Brand

$129.00

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$ 0.65

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12.24%

When you buy 1 container of Phoslo 667mg for $129.00 at Canada Drugs compared to the max price for 200 capsule of $147.00.

Canada Drugs Pharmacy is certified by

1 container (200 capsule): Phoslo 667mg: $129.00

Regular Shipping:: $0.00

Coupon Discount: $32.25

Total:: $96.75

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Phoslo Prices from JanDrugs

Phoslo 667mg

200 capsule
Brand

$129.00

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$ 0.65

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12.24%

When you buy 1 container of Phoslo 667mg for $129.00 at JanDrugs compared to the max price for 200 capsule of $147.00.

JanDrugs Pharmacy is certified by

1 container (200 capsule): Phoslo 667mg: $129.00

Regular Shipping:: $0.00

Coupon Discount: $12.9

Total:: $116.1

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Phoslo Prices from CanadianPharmacyKing

Phoslo 667 mg

400
Brand

$265.00

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$ 0.66

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0.00%

When you buy 1 container of Phoslo 667 mg for $265.00 at CanadianPharmacyKing compared to the max price for 400 of $265.00.

CanadianPharmacyKing Pharmacy is certified by

1 container (400): Phoslo 667 mg: $265.00

Regular Shipping:: $10.00

Total:: $275

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Phoslo Prices from CanadianPharmacyKing

Phoslo 667 mg

200
Brand

$140.00

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$ 0.70

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4.76%

When you buy 1 container of Phoslo 667 mg for $140.00 at CanadianPharmacyKing compared to the max price for 200 of $147.00.

CanadianPharmacyKing Pharmacy is certified by

1 container (200): Phoslo 667 mg: $140.00

Regular Shipping:: $10.00

Total:: $150

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Phoslo Prices from Canadian Pharmacy Meds

PhosLo 667mg

200
Brand

$147.00

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$ 0.74

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0.00%

When you buy 1 container of PhosLo 667mg for $147.00 at Canadian Pharmacy Meds compared to the max price for 200 of $147.00.

Canadian Pharmacy Meds Pharmacy is certified by

1 container (200): PhosLo 667mg: $147.00

Regular Shipping:: $10.00

Coupon Discount: $15.7

Total:: $141.3

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Phoslo Information

Product Code: 59730-6401

Company Name: Cardinal Health

Dosage From: TABLET

Strength: 667 mg

Phoslo (Calcium acetate) Description

Each white round tablet (stamped “BRA200”) contains 667 mg calcium acetate, USP (anhydrous; Ca(CHCOO); MW=158.17 grams) equal to 169 mg (8.45 mEq) calcium, and 10 mg of the inert binder, polyethylene glycol 8000 NF. Phoslo (Calcium acetate) Tablets (calcium acetate) are administered orally for the control of hyperphosphatemia in end stage renal failure.

Phoslo (Calcium acetate) Clinical Pharmacology

Patients with advanced renal insufficiency (creatinine clearance less than 30 mL/min) exhibit phosphate retention and some degree of hyperphosphatemia. The retention of phosphate plays a pivotal role in causing secondary hyperparathyroidism associated with osteodystrophy, and soft-tissue calcification. The mechanism by which phosphate retention leads to hyperparathyroidism is not clearly delineated. Therapeutic efforts directed toward the control of hyperphosphatemia include reduction in the dietary intake of phosphate, inhibition of absorption of phosphate in the intestine with phosphate binders, and removal of phosphate from the body by more efficient methods of dialysis. The rate of removal of phosphate by dietary manipulation or by dialysis is insufficient. Dialysis patients absorb 40% to 80% of dietary phosphorus. Therefore, the fraction of dietary phosphate absorbed from the diet needs to be reduced by using phosphate binders in most renal failure patients on maintenance dialysis. Calcium acetate (Phoslo (Calcium acetate) ) when taken with meals, combines with dietary phosphate to form insoluble calcium phosphate which is excreted in the feces. Maintenance of serum phosphorus below 6.0 mg/dl is generally considered as a clinically acceptable outcome of treatment with phosphate binders. Phoslo (Calcium acetate) is highly soluble at neutral pH, making the calcium readily available for binding to phosphate in the proximal small intestine. Orally administered calcium acetate from pharmaceutical dosage forms has been demonstrated to be systemically absorbed up to approximately 40% under fasting conditions and up to approximately 30% under nonfasting conditions. This range represents data from both healthy subjects and renal dialysis patients under various conditions.

Phoslo (Calcium acetate) Indications And Usage

Phoslo (Calcium acetate) is indicated for the control of hyperphosphatemia in end stage renal failure and does not promote aluminum absorption.

Phoslo (Calcium acetate) Contraindications

Patients with hypercalcemia.

Phoslo (Calcium acetate) Warnings

Patients with end stage renal failure may develop hypercalcemia when given calcium with meals. No other calcium supplements should be given concurrently with Phoslo (Calcium acetate) .

Progressive hypercalcemia due to overdose of Phoslo (Calcium acetate) may be severe as to require emergency measures. Chronic hypercalcemia may lead to vascular calcification, and other soft-tissue calcification. The serum calcium level should be monitored twice weekly during the early dose adjustment period. The serum calcium times phosphate (CaXP) product should not be allowed to exceed 66. Radiographic evaluation of suspect anatomical region may be helpful in early detection of soft-tissue calcification.

Phoslo (Calcium acetate) Adverse Reactions

In clinical studies, patients have occasionally experienced nausea during Phoslo (Calcium acetate) therapy. Hypercalcemia may occur during treatment with Phoslo (Calcium acetate) . Mild hypercalcemia (Ca>10.5mg/dL) may be asymptomatic or manifest itself as constipation, anorexia, nausea and vomiting. More severe hypercalcemia (Ca>12mg/dl) is associated with confusion, delirium, stupor and coma. Mild hypercalcemia is easily controlled by reducing the Phoslo (Calcium acetate) dose or temporarily discontinuing therapy. Severe hypercalcemia can be treated by acute hemodialysis and discontinuing Phoslo (Calcium acetate) therapy. Decreasing dialysate calcium concentration could reduce the incidence and severity of Phoslo (Calcium acetate) induced hypercalcemia. The long-term effect of Phoslo (Calcium acetate) on the progression of vascular or soft-tissue calcification has not been determined.

Isolated cases of pruritus have been reported which may represent allergic reactions.

Phoslo (Calcium acetate) Overdosage

Administration of Phoslo (Calcium acetate) in excess of the appropriate daily dosage can cause severe hypercalcemia (See ).

Phoslo (Calcium acetate) Dosage And Administration

The recommended initial dose of Phoslo (Calcium acetate) for the adult dialysis patient is 2 tablets with each meal. The dosage may be increased gradually to bring the serum phosphate value below 6 mg/dl, as long as hypercalcemia does not develop. Most patients require 3-4 tablets with each meal.

Phoslo (Calcium acetate) How Supplied

In tablet form for oral administration. Each white round tablet contains 667 mg calcium acetate (anhydrous Ca(CHCOO); MW=158.17 grams) equal to 169 mg (8.45 mEq) calcium, and 10 mg of the inert binder, polyethylene glycol 8000.

Tablets NDC 59730-6401-1 Bottles of 200