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Iopidine Price Comparison

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Iopidine Prices from JanDrugs

Iopidine 0.5%

15 ml
Brand

$109.65

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$ 7.31

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0.00%
When you buy 1 container of Iopidine 0.5% for $109.65 at JanDrugs compared to the max price for 15 ml of $109.65.
JanDrugs Pharmacy is certified by
1 container (15 ml): Iopidine 0.5%
$109.65
Regular Shipping:
$0.00
Coupon Discount
$10.965
Total:
$98.685
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Iopidine Prices from Canada Drugs

Iopidine 0.5%

15 ml
Brand

$109.65

viewdetail

$ 7.31

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0.00%
When you buy 1 container of Iopidine 0.5% for $109.65 at Canada Drugs compared to the max price for 15 ml of $109.65.
Canada Drugs Pharmacy is certified by
1 container (15 ml): Iopidine 0.5%
$109.65
Regular Shipping:
$0.00
Coupon Discount
$27.4125
Total:
$82.2375
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Iopidine Prices from Online Pharmacies Canada

Iopidine Eyedrops 0.50%

5 Ml
Brand

$38.79

viewdetail

$ 7.76

Go To STORE
29.47%
When you buy 1 container of Iopidine Eyedrops 0.50% for $38.79 at Online Pharmacies Canada compared to the max price for 5 Ml of $55.00.
Online Pharmacies Canada Pharmacy is certified by
1 container (5 Ml): Iopidine Eyedrops 0.50%
$38.79
Regular Shipping:
$9.95
Total:
$48.74
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Iopidine Prices from Online Pharmacies Canada

Iopidine 0.50%

5 Ml
Brand

$38.79

viewdetail

$ 7.76

Go To STORE
29.47%
When you buy 1 container of Iopidine 0.50% for $38.79 at Online Pharmacies Canada compared to the max price for 5 Ml of $55.00.
Online Pharmacies Canada Pharmacy is certified by
1 container (5 Ml): Iopidine 0.50%
$38.79
Regular Shipping:
$9.95
Total:
$48.74
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Iopidine Prices from Quality Prescription Drugs

Iopidine 0.50%

5 Ml
Brand

$38.89

viewdetail

$ 7.78

Go To STORE
29.29%
When you buy 1 container of Iopidine 0.50% for $38.89 at Quality Prescription Drugs compared to the max price for 5 Ml of $55.00.
Quality Prescription Drugs Pharmacy is certified by
1 container (5 Ml): Iopidine 0.50%
$38.89
Regular Shipping:
$9.00
Total:
$47.89
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Iopidine Prices from Quality Prescription Drugs

Iopidine Eyedrops 0.50%

5 Ml
Brand

$38.89

viewdetail

$ 7.78

Go To STORE
29.29%
When you buy 1 container of Iopidine Eyedrops 0.50% for $38.89 at Quality Prescription Drugs compared to the max price for 5 Ml of $55.00.
Quality Prescription Drugs Pharmacy is certified by
1 container (5 Ml): Iopidine Eyedrops 0.50%
$38.89
Regular Shipping:
$9.00
Total:
$47.89
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Iopidine Prices from Pharma Passport

Iopidine Eyedrops 0.50%

5 Ml
Brand

$38.99

viewdetail

$ 7.80

Go To STORE
29.11%
When you buy 1 container of Iopidine Eyedrops 0.50% for $38.99 at Pharma Passport compared to the max price for 5 Ml of $55.00.
1 container (5 Ml): Iopidine Eyedrops 0.50%
$38.99
Regular Shipping:
$9.95
Total:
$48.94
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Iopidine Prices from Pharma Passport

Iopidine 0.50%

5 Ml
Brand

$38.99

viewdetail

$ 7.80

Go To STORE
29.11%
When you buy 1 container of Iopidine 0.50% for $38.99 at Pharma Passport compared to the max price for 5 Ml of $55.00.
1 container (5 Ml): Iopidine 0.50%
$38.99
Regular Shipping:
$9.95
Total:
$48.94
Go To Store

Iopidine Prices from Online Canadian Pharmacy

Iopidine Eyedrops 0.50%

5 Ml
Brand

$41.02

viewdetail

$ 8.20

Go To STORE
25.42%
When you buy 1 container of Iopidine Eyedrops 0.50% for $41.02 at Online Canadian Pharmacy compared to the max price for 5 Ml of $55.00.
1 container (5 Ml): Iopidine Eyedrops 0.50%
$41.02
Regular Shipping:
$0.00
Total:
$41.02
Go To Store

Iopidine Prices from JanDrugs

Iopidine 0.5%

5 ml
Brand

$41.55

viewdetail

$ 8.31

Go To STORE
24.45%
When you buy 1 container of Iopidine 0.5% for $41.55 at JanDrugs compared to the max price for 5 ml of $55.00.
JanDrugs Pharmacy is certified by
1 container (5 ml): Iopidine 0.5%
$41.55
Regular Shipping:
$0.00
Coupon Discount
$4.155
Total:
$37.395
Go To Store

Iopidine Prices from Canada Drugs

Iopidine 0.5%

5 ml
Brand

$41.55

viewdetail

$ 8.31

Go To STORE
24.45%
When you buy 1 container of Iopidine 0.5% for $41.55 at Canada Drugs compared to the max price for 5 ml of $55.00.
Canada Drugs Pharmacy is certified by
1 container (5 ml): Iopidine 0.5%
$41.55
Regular Shipping:
$0.00
Coupon Discount
$10.3875
Total:
$31.1625
Go To Store

Iopidine Prices from DoctorSolve

Iopidine 0.50%

5 Ml
Brand

$55.00

viewdetail

$ 11.00

Go To STORE
0.00%
When you buy 1 container of Iopidine 0.50% for $55.00 at DoctorSolve compared to the max price for 5 Ml of $55.00.
DoctorSolve Pharmacy is certified by
1 container (5 Ml): Iopidine 0.50%
$55.00
Regular Shipping:
$9.95
Coupon Discount
$16.2375
Total:
$48.7125
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Iopidine Prices from PrescriptionPoint

Iopidine Eyedrops 0.50%

5 Ml
Brand

$55.00

viewdetail

$ 11.00

Go To STORE
0.00%
When you buy 1 container of Iopidine Eyedrops 0.50% for $55.00 at PrescriptionPoint compared to the max price for 5 Ml of $55.00.
PrescriptionPoint Pharmacy is certified by
1 container (5 Ml): Iopidine Eyedrops 0.50%
$55.00
Regular Shipping:
$9.95
Total:
$64.95
Go To Store

Iopidine Prices from MapleLeafMeds

Iopidine 0.50%

5 Ml
Brand

$55.00

viewdetail

$ 11.00

Go To STORE
0.00%
When you buy 1 container of Iopidine 0.50% for $55.00 at MapleLeafMeds compared to the max price for 5 Ml of $55.00.
MapleLeafMeds Pharmacy is certified by
1 container (5 Ml): Iopidine 0.50%
$55.00
Regular Shipping:
$9.95
Total:
$64.95
Go To Store

Iopidine Prices from DoctorSolve

Iopidine Eyedrops 0.50%

5 Ml
Brand

$55.00

viewdetail

$ 11.00

Go To STORE
0.00%
When you buy 1 container of Iopidine Eyedrops 0.50% for $55.00 at DoctorSolve compared to the max price for 5 Ml of $55.00.
DoctorSolve Pharmacy is certified by
1 container (5 Ml): Iopidine Eyedrops 0.50%
$55.00
Regular Shipping:
$9.95
Coupon Discount
$16.2375
Total:
$48.7125
Go To Store

Iopidine Prices from PrescriptionPoint

Iopidine 0.50%

5 Ml
Brand

$55.00

viewdetail

$ 11.00

Go To STORE
0.00%
When you buy 1 container of Iopidine 0.50% for $55.00 at PrescriptionPoint compared to the max price for 5 Ml of $55.00.
PrescriptionPoint Pharmacy is certified by
1 container (5 Ml): Iopidine 0.50%
$55.00
Regular Shipping:
$9.95
Total:
$64.95
Go To Store

Iopidine Prices from MapleLeafMeds

Iopidine Eyedrops 0.50%

5 Ml
Brand

$55.00

viewdetail

$ 11.00

Go To STORE
0.00%
When you buy 1 container of Iopidine Eyedrops 0.50% for $55.00 at MapleLeafMeds compared to the max price for 5 Ml of $55.00.
MapleLeafMeds Pharmacy is certified by
1 container (5 Ml): Iopidine Eyedrops 0.50%
$55.00
Regular Shipping:
$9.95
Total:
$64.95
Go To Store

Iopidine Prices from Canadian Pharmacy Meds

Iopidine Eye Drops 1 x 5ml 0.005

1
Brand

$31.00

viewdetail

$ 31.00

Go To STORE
27.91%
When you buy 1 container of Iopidine Eye Drops 1 x 5ml 0.005 for $31.00 at Canadian Pharmacy Meds compared to the max price for 1 of $43.00.
Canadian Pharmacy Meds Pharmacy is certified by
1 container (1): Iopidine Eye Drops 1 x 5ml 0.005
$31.00
Regular Shipping:
$10.00
Coupon Discount
$4.1
Total:
$36.9
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Iopidine Prices from CanadianPharmacyKing

Iopidine 0.5 %/5 ml

3
Brand

$99.00

viewdetail

$ 33.00

Go To STORE
0.00%
When you buy 1 container of Iopidine 0.5 %/5 ml for $99.00 at CanadianPharmacyKing compared to the max price for 3 of $99.00.
CanadianPharmacyKing Pharmacy is certified by
1 container (3): Iopidine 0.5 %/5 ml
$99.00
Regular Shipping:
$10.00
Total:
$109
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Iopidine Prices from CanadianPharmacyKing

Iopidine 0.5 %/5 ml

1
Brand

$43.00

viewdetail

$ 43.00

Go To STORE
0.00%
When you buy 1 container of Iopidine 0.5 %/5 ml for $43.00 at CanadianPharmacyKing compared to the max price for 1 of $43.00.
CanadianPharmacyKing Pharmacy is certified by
1 container (1): Iopidine 0.5 %/5 ml
$43.00
Regular Shipping:
$10.00
Total:
$53
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Iopidine Information

Product Code
0065-0665
Company Name
Alcon Laboratories, Inc.
Dosage From
SOLUTION
Strength
5 mg
Active Ingredient
APRACLONIDINE HYDROCHLORIDE

Iopidine (Apraclonidine) Description

Iopidine (Apraclonidine) ® 0.5% Ophthalmic Solution contains apraclonidine hydrochloride, an alpha adrenergic agonist, in a sterile isotonic solution for topical application to the eye. Apraclonidine hydrochloride is a white to off-white powder and is highly soluble in water. Its chemical name is 2-[(4-amino-2,6 dichlorophenyl) imino]imidazolidine monohydrochloride with an empirical formula of CHClN and a molecular weight of 281.57. The chemical structure of apraclonidine hydrochloride is:

Iopidine (Apraclonidine) Clinical Pharmacology

Apraclonidine hydrochloride is a relatively selective alpha-2-adrenergic agonist. When instilled in the eye, Iopidine (Apraclonidine) 0.5% Ophthalmic Solution, has the action of reducing elevated, as well as normal, intraocular pressure (IOP), whether or not accompanied by glaucoma. Ophthalmic apraclonidine has minimal effect on cardiovascular parameters.

Elevated IOP presents a major risk factor in glaucomatous field loss. The higher the level of IOP, the greater the likelihood of optic nerve damage and visual field loss. Iopidine (Apraclonidine) 0.5% Ophthalmic Solution has the action of reducing IOP. The onset of action of apraclonidine can usually be noted within one hour, and maximum IOP reduction occurs about three hours after instillation. Aqueous fluorophotometry studies demonstrate that apraclonidine's predominant mechanism of action is reduction of aqueous flow via stimulation of the alpha-adrenergic system.

Repeated dose-response and comparative studies (0.125% - 1.0% apraclonidine) demonstrate that 0.5% apraclonidine is at the top of the dose/response IOP reduction curve.

The clinical utility of Iopidine (Apraclonidine) 0.5% Ophthalmic Solution is most apparent for those glaucoma patients on maximally tolerated medical therapy. Patients on maximally tolerated medical therapy with uncontrolled IOP and scheduled to undergo laser trabeculoplasty or trabeculectomy surgery were enrolled into a doublemasked, placebo-controlled, multi-center clinical trial to determine if Iopidine (Apraclonidine) 0.5% Ophthalmic Solution, dosed three times daily (TID), could delay the need for surgery for up to three months.

All patients enrolled into this trial had advanced glaucoma and were undergoing maximally tolerated medical therapy, i.e., patients were using combinations of a topical beta blocker, sympathomimetics, parasympathomimetics and oral carbonic anhydrase inhibitors. Patients were considered to be treatment failures in this study if, in the opinion of the investigators, their IOP was uncontrolled by the masked study medication or there was evidence of further optic nerve damage or visual field loss, and surgery was indicated. Of 171 patients receiving masked medication, 84 were treated with Iopidine (Apraclonidine) 0.5% Ophthalmic Solution and 87 were treated with placebo (apraclonidine vehicle).

Apraclonidine treatment resulted in a significantly greater percentage of treatment successes compared to patients treated with placebo. In this placebo-controlled maximum therapy trial, 14.3% of patients treated with Iopidine (Apraclonidine) 0.5% Ophthalmic Solution were discontinued

due to adverse events, primarily allergic-like reactions (12.9%).

The IOP lowering efficacy of Iopidine (Apraclonidine) 0.5% Ophthalmic Solution diminishes over time in some patients. This loss of effect, or tachyphylaxis, appears to be an individual occurrence with a variable time of onset and should be closely monitored.

An unpredictable decrease of IOP control in some patients and incidence of ocular allergic responses and systemic side effects may limit the utility of Iopidine (Apraclonidine) 0.5% Ophthalmic Solution. However, patients on maximally tolerated medical therapy may still benefit from the additional IOP reduction provided by the shortterm use of Iopidine (Apraclonidine) 0.5% Ophthalmic Solution.

Topical use of Iopidine (Apraclonidine) 0.5% Ophthalmic Solution leads to systemic absorption. Studies of Iopidine (Apraclonidine) 0.5% Ophthalmic Solution dosed one drop three times a day in both eyes for 10 days in normal volunteers yielded mean peak and trough concentrations of 0.9 ng/mL and 0.5 ng/mL, respectively. The half-life of Iopidine (Apraclonidine) ® 0.5% (apraclonidine ophthalmic solution) was calculated to be 8 hours.

Iopidine (Apraclonidine) ® 0.5% Ophthalmic Solution, because of its alpha adrenergic activity, is a vasoconstrictor. Single dose ocular blood flow studies in monkeys, using the microsphere technique, demonstrated a reduced blood flow for the anterior segment; however, no reduction in blood flow was observed in the posterior segment of the eye after a topical dose of Iopidine (Apraclonidine) 0.5% Ophthalmic Solution. Ocular blood flow studies have not been conducted in humans.

Iopidine (Apraclonidine) Indications And Usage

Iopidine (Apraclonidine) 0.5% Ophthalmic Solution is indicated for short-term adjunctive therapy in patients on maximally tolerated medical therapy who require additional IOP reduction. Patients on maximally tolerated medical therapy who are treated with Iopidine (Apraclonidine) 0.5% Ophthalmic Solution to delay surgery should have frequent followup examinations and treatment should be discontinued if the intraocular pressure rises significantly.

The addition of Iopidine (Apraclonidine) 0.5% Ophthalmic Solution to patients already using two aqueous suppressing drugs (i.e., beta-blocker plus carbonic anhydrase inhibitor) as part of their maximally tolerated medical therapy may not provide additional benefit. This is because Iopidine (Apraclonidine) 0.5% Ophthalmic Solution is an aqueous suppressing drug and the addition of a third aqueous suppressant may not significantly reduce IOP.

The IOP lowering efficacy of Iopidine (Apraclonidine) 0.5% Ophthalmic Solution diminishes over time in some patients. This loss of effect, or tachyphylaxis, appears to be an individual occurrence with a variable time of onset and should be closely monitored. The benefit for most patients is less than one month.

Iopidine (Apraclonidine) Contraindications

Iopidine (Apraclonidine) 0.5% Ophthalmic Solution is contraindicated in patients with hypersensitivity to apraclonidine or any other component of this medication, as well as systemic clonidine. It is also contraindicated in patients receiving monoamine oxidase inhibitors (MAO inhibitors).

Iopidine (Apraclonidine) Warnings

Not for injection or oral ingestion.

FOR TOPICAL OPHTHALMIC USE ONLY.

Iopidine (Apraclonidine) Precautions: General

Glaucoma patients on maximally tolerated medical therapy who are treated with Iopidine (Apraclonidine) 0.5% Ophthalmic Solution to delay surgery should have their visual fields monitored periodically.

Although the topical use of Iopidine (Apraclonidine) 0.5% Ophthalmic Solution has not been studied in renal failure patients, structurally related clonidine undergoes a significant increase in half-life in patients with severe renal impairment. Close monitoring of cardiovascular parameters in patients with impaired renal function is advised if they are candidates for topical apraclonidine therapy. Close monitoring of cardiovascular parameters in patients with impaired liver function is also advised as the systemic dosage form of clonidine is partly metabolized in the liver.

While the topical administration of Iopidine (Apraclonidine) 0.5% Ophthalmic Solution had minimal effect on heart rate or blood pressure in clinical studies evaluating glaucoma patients, the preclinical pharmacology profile of this drug suggests that caution should be observed in treating patients with severe, uncontrolled cardiovascular disease, including hypertension.

Iopidine (Apraclonidine) 0.5% Ophthalmic Solution should be used with caution in patients with coronary insufficiency, recent myocardial infarction, cerebrovascular disease, chronic renal failure, Raynaud's disease, or thromboangiitis obliterans. Caution and monitoring of depressed patients are advised since apraclonidine has been infrequently associated with depression.

Apraclonidine can cause dizziness and somnolence. Patients who engage in hazardous activities requiring mental alertness should be warned of the potential for a decrease in mental alertness while using apraclonidine.

Topical ocular administration of two drops of 0.5, 1.0 and 1.5% apraclonidine ophthalmic solution to New Zealand albino rabbits three times daily for one month resulted in sporadic and transient instances of minimal corneal edema in the 1.5% group only; no histopathological changes were noted in those eyes.

Use of Iopidine (Apraclonidine) 0.5% Ophthalmic Solution can lead to an allergic-like reaction characterized wholly or in part by the symptoms of hyperemia, pruritus, discomfort, tearing, foreign body sensation, and edema of the lids and conjunctiva. If ocular allergic-like symptoms occur, Iopidine (Apraclonidine) 0.5% (apraclonidine ophthalmic solution) therapy should be discontinued.

Iopidine (Apraclonidine) Patient Information

Do not touch dropper tip to any surface as this may contaminate the contents.

Iopidine (Apraclonidine) Drug Interactions

Apraclonidine should not be used in patients receiving MAO inhibitors. (See CONTRAINDICATIONS). Although no specific drug interactions with topical glaucoma drugs or systemic medications were identified in clinical studies of Iopidine (Apraclonidine) ® 0.5% Ophthalmic Solution, the possibility of an additive or potentiating effect with CNS depressants (alcohol, barbiturates, opiates, sedatives, anesthetics) should be considered. Tricyclic antidepressants have been reported to blunt the hypotensive effect of systemic clonidine. It is not known whether the concurrent use of these agents with apraclonidine can lead to a reduction in IOP lowering effect. No data on the level of circulating catecholamines after apraclonidine withdrawal are available. Caution, however, is advised in patients taking tricyclic antidepressants which can affect the metabolism and uptake of circulating amines.

An additive hypotensive effect has been reported with the combination of systemic clonidine and neuroleptic therapy. Systemic clonidine may inhibit the production of catecholamines in response to insulin-induced hypoglycemia and mask the signs and symptoms of hypoglycemia.

Since apraclonidine may reduce pulse and blood pressure, caution in using drugs such as beta-blockers (ophthalmic and systemic), antihypertensives, and cardiac glycosides is advised. Patients using cardiovascular drugs concurrently with Iopidine (Apraclonidine) 0.5% Ophthalmic Solution should have pulse and blood pressures frequently monitored. Caution should be exercised with simultaneous use of clonidine and other similar pharmacologic agents.

Iopidine (Apraclonidine) Carcinogenesis, Mutagenesis, Impairment Of Fertility

No significant change in tumor incidence or type was observed following two years of oral administration of apraclonidine HCl to rats and mice at dosages of 1.0 and 0.6 mg/kg, up to 20 and 12 times, respectively, the maximum dose recommended for human topical ocular use.

Apraclonidine HCl was not mutagenic in a series of mutagenicity tests, including the Ames test, a mouse lymphoma forward mutation assay, a chromosome aberration assay in cultured Chinese hamster ovary (CHO) cells, a sister chromatid exchange assay in CHO cells, and a cell transformation assay.

An mouse micronucleus assay conducted with apraclonidine HCl also provided no evidence of mutagenicity.

Reproduction and fertility studies in rats showed no adverse effect on male or female fertility at a dose of 0.5 mg/kg (5 to 10 times the maximum recommended human dose).

Iopidine (Apraclonidine) Pregnancy

Pregnancy Category C:

Iopidine (Apraclonidine) Nursing Mothers

It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when Iopidine (Apraclonidine) 0.5% Ophthalmic Solution is administered to a nursing woman.

Iopidine (Apraclonidine) Pediatric Use

Safety and effectiveness in pediatric patients have not been established.

Iopidine (Apraclonidine) Geriatric Use

No overall differences in safety or effectiveness have been observed between elderly and younger patients.

Iopidine (Apraclonidine) Adverse Reactions

In clinical studies the overall discontinuation rate related to Iopidine (Apraclonidine) 0.5% Ophthalmic Solution was 15%. The most commonly reported events leading to discontinuation included (in decreasing order of frequency) hyperemia, pruritus, tearing, discomfort, lid edema, dry mouth, and foreign body sensation.

The following adverse reactions (incidences) were reported in clinical studies of Iopidine (Apraclonidine) 0.5% (apraclonidine ophthalmic solution) as being possibly, probably, or definitely related to therapy:

The following adverse reactions were reported in 5 to 15% of the patients: discomfort, hyperemia, and puritus. The following adverse reactions were reported in 1 to 5% of the patients: blanching, blurred vision, conjunctivitis, discharge, dry eye, foreign body sensation, lid edema, and tearing.

The following adverse reactions were reported in less than 1% of the patients: abnormal vision, blepharitis, blepharoconjunctivitis, conjunctival edema, conjunctival follicles, corneal erosion, corneal infiltrate, corneal staining, edema, irritation, keratitis, keratopathy, lid disorder, lid erythema, lid margin crusting, lid retraction, lid scales, pain, photophobia.

Dry mouth occurred in approximately 10% of the patients.

The following adverse reactions were reported in less than 3% of the patients: abnormal coordination, asthenia, arrhythmia, asthma, chest pain, constipation, contact dermatitis, depression, dermatitis, dizziness, dry nose, dyspnea, facial edema, headache, insomnia, malaise, myalgia, nausea, nervousness, paresthesia, parosmia, peripheral edema, pharyngitis, rhinitis, somnolence, and taste perversion.

Clinical practice: The following events have been identified during post-marketing use of Iopidine (Apraclonidine) ® 0.5% Ophthalmic Solution in clinical practice. Because they are reported voluntarily from a population of unknown size, estimates of frequency cannot be made. The events, which have been chosen for inclusion due to either their seriousness, frequency of reporting, possible causal connection to Iopidine (Apraclonidine) 0.5% Ophthalmic Solution, or a combination of these factors, include: bradycardia.

Iopidine (Apraclonidine) Overdosage

Ingestion of Iopidine (Apraclonidine) 0.5% Ophthalmic Solution has been reported to cause bradycardia, drowsiness, and hypothermia.

Accidental or intentional ingestion of oral clonidine has been reported to cause apnea, arrhythmias, asthenia, bradycardia, conduction defects, diminished or absent reflexes, dryness of the mouth, hypotension, hypothermia, hypoventilation, irritability, lethargy, miosis, pallor, respiratory depression, sedation or coma, seizure, somnolence, transient hypertension, and vomiting.

Treatment of an oral overdose includes supportive and symptomatic therapy; a patent airway should be maintained. Hemodialysis is of limited value since a maximum of 5% of circulating drug is removed.

Iopidine (Apraclonidine) Dosage And Administration

One to two drops of Iopidine (Apraclonidine) 0.5% Ophthalmic Solution should be instilled in the affected eye(s) three times daily. Since Iopidine (Apraclonidine) 0.5% Ophthalmic Solution will be used with other ocular glaucoma therapies, an approximate 5 minute interval between instillation of each medication should be practiced to prevent washout of the previous dose.

NOT FOR INJECTION INTO THE EYE. NOT FOR ORAL INGESTION.

Iopidine (Apraclonidine) How Supplied

Iopidine (Apraclonidine) 0.5% Ophthalmic Solution as base in a sterile, isotonic, aqueous solution containing apraclonidine hydrochloride.

Supplied in plastic ophthalmic DROP-TAINER® dispenser as follows:

5 mL 0065-0665-05

10 mL 0065-0665-10

Protect from freezing and light.

Fort Worth, Texas 76134 USA

December 2003 Printed in USA

©2003 Alcon, Inc.

      

Iopidine (Apraclonidine) Principal Display Panel

NDC 0065-0665-05

Alcon®

Iopidine (Apraclonidine) ®

0.5%

(apraclonidine

ophthalmic solution

0.5% as base

5 mL Sterile

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