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You are here:Home»Prescription Drugs A to Z»Ditropan

Ditropan Price Comparison

Buy Ditropan Online and Read Ditropan Reviews

Use eDrugSearch to check Ditropan price comparison results below and read verified Ditropan reviews before you buy Ditropan online. Simply click the "Buy Now" button or the "Pharmacy Logo" to buy Ditropan online from one of our licensed Canadian pharmacies.

*To refine your Ditropan price comparison search further click on the "All, Brand or Generic" tab so you can view all the Ditropan prices located within our database.

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Ditropan Prices from BuyLow Drugs

Ditropan syrp 5//5mg/ml

473
Brand

$69.00

viewdetail

$ 0.15

Go To STORE
21.02%
When you buy 1 container of Ditropan syrp 5//5mg/ml for $69.00 at BuyLow Drugs compared to the max price for 473 of $87.36.
1 container (473): Ditropan syrp 5//5mg/ml
$69.00
Regular Shipping:
$0.00
Total:
$69
Go To Store

Ditropan Prices from JanDrugs

Ditropan Syrup 5mg/5mL

473 ml
Brand

$87.36

viewdetail

$ 0.18

Go To STORE
0.00%
When you buy 1 container of Ditropan Syrup 5mg/5mL for $87.36 at JanDrugs compared to the max price for 473 ml of $87.36.
JanDrugs Pharmacy is certified by
1 container (473 ml): Ditropan Syrup 5mg/5mL
$87.36
Regular Shipping:
$0.00
Coupon Discount
$8.736
Total:
$78.624
Go To Store

Ditropan Prices from Canada Drugs

Ditropan Syrup 5MG/5ML

473 ml
Brand

$87.36

viewdetail

$ 0.18

Go To STORE
0.00%
When you buy 1 container of Ditropan Syrup 5MG/5ML for $87.36 at Canada Drugs compared to the max price for 473 ml of $87.36.
Canada Drugs Pharmacy is certified by
1 container (473 ml): Ditropan Syrup 5MG/5ML
$87.36
Regular Shipping:
$0.00
Coupon Discount
$21.84
Total:
$65.52
Go To Store

Ditropan Prices from Canada Drugs

Ditropan Elixir 2.5mg / 5 ml

150 ml
Brand

$57.36

viewdetail

$ 0.38

Go To STORE
0.00%
When you buy 1 container of Ditropan Elixir 2.5mg / 5 ml for $57.36 at Canada Drugs compared to the max price for 150 ml of $57.36.
Canada Drugs Pharmacy is certified by
1 container (150 ml): Ditropan Elixir 2.5mg / 5 ml
$57.36
Regular Shipping:
$0.00
Coupon Discount
$14.34
Total:
$43.02
Go To Store

Ditropan Prices from JanDrugs

Ditropan Elixir 2.5mg/5mL

150 ml
Brand

$57.36

viewdetail

$ 0.38

Go To STORE
0.00%
When you buy 1 container of Ditropan Elixir 2.5mg/5mL for $57.36 at JanDrugs compared to the max price for 150 ml of $57.36.
JanDrugs Pharmacy is certified by
1 container (150 ml): Ditropan Elixir 2.5mg/5mL
$57.36
Regular Shipping:
$0.00
Coupon Discount
$5.736
Total:
$51.624
Go To Store

Ditropan Prices from MapleLeafMeds

Ditropan 5mg

84
Brand

$45.00

viewdetail

$ 0.54

Go To STORE
24.48%
When you buy 1 container of Ditropan 5mg for $45.00 at MapleLeafMeds compared to the max price for 84 of $59.59.
MapleLeafMeds Pharmacy is certified by
1 container (84): Ditropan 5mg
$45.00
Regular Shipping:
$9.95
Total:
$54.95
Go To Store

Ditropan Prices from Quality Prescription Drugs

Ditropan 5mg

84
Brand

$50.00

viewdetail

$ 0.60

Go To STORE
16.09%
When you buy 1 container of Ditropan 5mg for $50.00 at Quality Prescription Drugs compared to the max price for 84 of $59.59.
Quality Prescription Drugs Pharmacy is certified by
1 container (84): Ditropan 5mg
$50.00
Regular Shipping:
$9.00
Total:
$59
Go To Store

Ditropan Prices from Online Pharmacies Canada

Ditropan 5mg

84
Brand

$50.25

viewdetail

$ 0.60

Go To STORE
15.67%
When you buy 1 container of Ditropan 5mg for $50.25 at Online Pharmacies Canada compared to the max price for 84 of $59.59.
Online Pharmacies Canada Pharmacy is certified by
1 container (84): Ditropan 5mg
$50.25
Regular Shipping:
$9.95
Total:
$60.2
Go To Store

Ditropan Prices from JanDrugs

Ditropan 5mg

100 tablet
Brand

$59.83

viewdetail

$ 0.60

Go To STORE
79.99%
When you buy 1 container of Ditropan 5mg for $59.83 at JanDrugs compared to the max price for 100 tablet of $299.00.
JanDrugs Pharmacy is certified by
1 container (100 tablet): Ditropan 5mg
$59.83
Regular Shipping:
$0.00
Coupon Discount
$5.983
Total:
$53.847
Go To Store

Ditropan Prices from Canada Drugs

Ditropan 5mg

100 tablet
Brand

$59.83

viewdetail

$ 0.60

Go To STORE
79.99%
When you buy 1 container of Ditropan 5mg for $59.83 at Canada Drugs compared to the max price for 100 tablet of $299.00.
Canada Drugs Pharmacy is certified by
1 container (100 tablet): Ditropan 5mg
$59.83
Regular Shipping:
$0.00
Coupon Discount
$14.9575
Total:
$44.8725
Go To Store

Ditropan Prices from Pharma Passport

Ditropan 5mg

84
Brand

$50.50

viewdetail

$ 0.60

Go To STORE
15.25%
When you buy 1 container of Ditropan 5mg for $50.50 at Pharma Passport compared to the max price for 84 of $59.59.
1 container (84): Ditropan 5mg
$50.50
Regular Shipping:
$9.95
Total:
$60.45
Go To Store

Ditropan Prices from PrescriptionPoint

Ditropan 5mg

84
Brand

$59.00

viewdetail

$ 0.70

Go To STORE
0.99%
When you buy 1 container of Ditropan 5mg for $59.00 at PrescriptionPoint compared to the max price for 84 of $59.59.
PrescriptionPoint Pharmacy is certified by
1 container (84): Ditropan 5mg
$59.00
Regular Shipping:
$9.95
Total:
$68.95
Go To Store

Ditropan Prices from DoctorSolve

Ditropan 5mg

84
Brand

$59.00

viewdetail

$ 0.70

Go To STORE
0.99%
When you buy 1 container of Ditropan 5mg for $59.00 at DoctorSolve compared to the max price for 84 of $59.59.
DoctorSolve Pharmacy is certified by
1 container (84): Ditropan 5mg
$59.00
Regular Shipping:
$9.95
Coupon Discount
$17.2375
Total:
$51.7125
Go To Store

Ditropan Prices from Online Canadian Pharmacy

Ditropan 5mg

84
Brand

$59.59

viewdetail

$ 0.71

Go To STORE
0.00%
When you buy 1 container of Ditropan 5mg for $59.59 at Online Canadian Pharmacy compared to the max price for 84 of $59.59.
1 container (84): Ditropan 5mg
$59.59
Regular Shipping:
$0.00
Total:
$59.59
Go To Store

Ditropan Prices from CanadianPharmacyKing

Ditropan 5 mg

180
Brand

$185.00

viewdetail

$ 1.03

Go To STORE
54.77%
When you buy 1 container of Ditropan 5 mg for $185.00 at CanadianPharmacyKing compared to the max price for 180 of $409.00.
CanadianPharmacyKing Pharmacy is certified by
1 container (180): Ditropan 5 mg
$185.00
Regular Shipping:
$10.00
Total:
$195
Go To Store

Ditropan Prices from Canada Drug Center

Ditropan XL 5mg

900
Brand

$979.00

viewdetail

$ 1.09

Go To STORE
42.88%
When you buy 1 container of Ditropan XL 5mg for $979.00 at Canada Drug Center compared to the max price for 900 of $1714.00.
Canada Drug Center Pharmacy is certified by
1 container (900): Ditropan XL 5mg
$979.00
Regular Shipping:
$9.99
Coupon Discount
$98.899
Total:
$890.091
Go To Store

Ditropan Prices from Canadian Pharmacy Meds

Ditropan XL 5mg

900
Brand

$980.00

viewdetail

$ 1.09

Go To STORE
42.82%
When you buy 1 container of Ditropan XL 5mg for $980.00 at Canadian Pharmacy Meds compared to the max price for 900 of $1714.00.
Canadian Pharmacy Meds Pharmacy is certified by
1 container (900): Ditropan XL 5mg
$980.00
Regular Shipping:
$10.00
Coupon Discount
$99
Total:
$891
Go To Store

Ditropan Prices from Canada Drug Center

Ditropan XL 5mg

720
Brand

$792.00

viewdetail

$ 1.10

Go To STORE
42.61%
When you buy 1 container of Ditropan XL 5mg for $792.00 at Canada Drug Center compared to the max price for 720 of $1380.00.
Canada Drug Center Pharmacy is certified by
1 container (720): Ditropan XL 5mg
$792.00
Regular Shipping:
$9.99
Coupon Discount
$80.199
Total:
$721.791
Go To Store

Ditropan Prices from Canadian Pharmacy Meds

Ditropan XL 5mg

720
Brand

$793.00

viewdetail

$ 1.10

Go To STORE
42.54%
When you buy 1 container of Ditropan XL 5mg for $793.00 at Canadian Pharmacy Meds compared to the max price for 720 of $1380.00.
Canadian Pharmacy Meds Pharmacy is certified by
1 container (720): Ditropan XL 5mg
$793.00
Regular Shipping:
$10.00
Coupon Discount
$80.3
Total:
$722.7
Go To Store

Ditropan Prices from MapleLeafMeds

Ditropan 5mg

360
Brand

$405.00

viewdetail

$ 1.13

Go To STORE
50.61%
When you buy 1 container of Ditropan 5mg for $405.00 at MapleLeafMeds compared to the max price for 360 of $820.00.
MapleLeafMeds Pharmacy is certified by
1 container (360): Ditropan 5mg
$405.00
Regular Shipping:
$9.95
Total:
$414.95
Go To Store

Ditropan Prices from MapleLeafMeds

Ditropan XL 5mg

360
Brand

$405.00

viewdetail

$ 1.13

Go To STORE
50.61%
When you buy 1 container of Ditropan XL 5mg for $405.00 at MapleLeafMeds compared to the max price for 360 of $820.00.
MapleLeafMeds Pharmacy is certified by
1 container (360): Ditropan XL 5mg
$405.00
Regular Shipping:
$9.95
Total:
$414.95
Go To Store

Ditropan Prices from Canada Drug Center

Ditropan XL 5mg

360
Brand

$419.00

viewdetail

$ 1.16

Go To STORE
48.90%
When you buy 1 container of Ditropan XL 5mg for $419.00 at Canada Drug Center compared to the max price for 360 of $820.00.
Canada Drug Center Pharmacy is certified by
1 container (360): Ditropan XL 5mg
$419.00
Regular Shipping:
$9.99
Coupon Discount
$42.899
Total:
$386.091
Go To Store

Ditropan Prices from Canadian Pharmacy Meds

Ditropan XL 5mg

360
Brand

$420.00

viewdetail

$ 1.17

Go To STORE
48.78%
When you buy 1 container of Ditropan XL 5mg for $420.00 at Canadian Pharmacy Meds compared to the max price for 360 of $820.00.
Canadian Pharmacy Meds Pharmacy is certified by
1 container (360): Ditropan XL 5mg
$420.00
Regular Shipping:
$10.00
Coupon Discount
$43
Total:
$387
Go To Store

Ditropan Prices from Quality Prescription Drugs

Ditropan XL 5mg

360
Brand

$427.00

viewdetail

$ 1.19

Go To STORE
47.93%
When you buy 1 container of Ditropan XL 5mg for $427.00 at Quality Prescription Drugs compared to the max price for 360 of $820.00.
Quality Prescription Drugs Pharmacy is certified by
1 container (360): Ditropan XL 5mg
$427.00
Regular Shipping:
$9.00
Total:
$436
Go To Store

Ditropan Prices from Quality Prescription Drugs

Ditropan 5mg

360
Brand

$427.00

viewdetail

$ 1.19

Go To STORE
47.93%
When you buy 1 container of Ditropan 5mg for $427.00 at Quality Prescription Drugs compared to the max price for 360 of $820.00.
Quality Prescription Drugs Pharmacy is certified by
1 container (360): Ditropan 5mg
$427.00
Regular Shipping:
$9.00
Total:
$436
Go To Store

Ditropan Prices from Online Pharmacies Canada

Ditropan 5mg

360
Brand

$429.13

viewdetail

$ 1.19

Go To STORE
47.67%
When you buy 1 container of Ditropan 5mg for $429.13 at Online Pharmacies Canada compared to the max price for 360 of $820.00.
Online Pharmacies Canada Pharmacy is certified by
1 container (360): Ditropan 5mg
$429.13
Regular Shipping:
$9.95
Total:
$439.08
Go To Store

Ditropan Prices from Online Pharmacies Canada

Ditropan XL 5mg

360
Brand

$429.13

viewdetail

$ 1.19

Go To STORE
47.67%
When you buy 1 container of Ditropan XL 5mg for $429.13 at Online Pharmacies Canada compared to the max price for 360 of $820.00.
Online Pharmacies Canada Pharmacy is certified by
1 container (360): Ditropan XL 5mg
$429.13
Regular Shipping:
$9.95
Total:
$439.08
Go To Store

Ditropan Prices from Pharma Passport

Ditropan XL 5mg

360
Brand

$431.28

viewdetail

$ 1.20

Go To STORE
47.40%
When you buy 1 container of Ditropan XL 5mg for $431.28 at Pharma Passport compared to the max price for 360 of $820.00.
1 container (360): Ditropan XL 5mg
$431.28
Regular Shipping:
$9.95
Total:
$441.23
Go To Store

Ditropan Prices from Pharma Passport

Ditropan 5mg

360
Brand

$431.28

viewdetail

$ 1.20

Go To STORE
47.40%
When you buy 1 container of Ditropan 5mg for $431.28 at Pharma Passport compared to the max price for 360 of $820.00.
1 container (360): Ditropan 5mg
$431.28
Regular Shipping:
$9.95
Total:
$441.23
Go To Store

Ditropan Prices from CanadianPharmacyKing

Ditropan 5 mg

90
Brand

$109.00

viewdetail

$ 1.21

Go To STORE
57.09%
When you buy 1 container of Ditropan 5 mg for $109.00 at CanadianPharmacyKing compared to the max price for 90 of $254.00.
CanadianPharmacyKing Pharmacy is certified by
1 container (90): Ditropan 5 mg
$109.00
Regular Shipping:
$10.00
Total:
$119
Go To Store

Ditropan Prices from MapleLeafMeds

Ditropan 5mg

90
Brand

$110.00

viewdetail

$ 1.22

Go To STORE
56.69%
When you buy 1 container of Ditropan 5mg for $110.00 at MapleLeafMeds compared to the max price for 90 of $254.00.
MapleLeafMeds Pharmacy is certified by
1 container (90): Ditropan 5mg
$110.00
Regular Shipping:
$9.95
Total:
$119.95
Go To Store

Ditropan Prices from MapleLeafMeds

Ditropan XL 5mg

90
Brand

$110.00

viewdetail

$ 1.22

Go To STORE
56.69%
When you buy 1 container of Ditropan XL 5mg for $110.00 at MapleLeafMeds compared to the max price for 90 of $254.00.
MapleLeafMeds Pharmacy is certified by
1 container (90): Ditropan XL 5mg
$110.00
Regular Shipping:
$9.95
Total:
$119.95
Go To Store

Ditropan Prices from Canada Drug Center

Ditropan XL 5mg

180
Brand

$231.00

viewdetail

$ 1.28

Go To STORE
43.52%
When you buy 1 container of Ditropan XL 5mg for $231.00 at Canada Drug Center compared to the max price for 180 of $409.00.
Canada Drug Center Pharmacy is certified by
1 container (180): Ditropan XL 5mg
$231.00
Regular Shipping:
$9.99
Coupon Discount
$24.099
Total:
$216.891
Go To Store

Ditropan Prices from Quality Prescription Drugs

Ditropan 5mg

90
Brand

$115.62

viewdetail

$ 1.28

Go To STORE
54.48%
When you buy 1 container of Ditropan 5mg for $115.62 at Quality Prescription Drugs compared to the max price for 90 of $254.00.
Quality Prescription Drugs Pharmacy is certified by
1 container (90): Ditropan 5mg
$115.62
Regular Shipping:
$9.00
Total:
$124.62
Go To Store

Ditropan Prices from Quality Prescription Drugs

Ditropan XL 5mg

90
Brand

$115.62

viewdetail

$ 1.28

Go To STORE
54.48%
When you buy 1 container of Ditropan XL 5mg for $115.62 at Quality Prescription Drugs compared to the max price for 90 of $254.00.
Quality Prescription Drugs Pharmacy is certified by
1 container (90): Ditropan XL 5mg
$115.62
Regular Shipping:
$9.00
Total:
$124.62
Go To Store

Ditropan Prices from Canadian Pharmacy Meds

Ditropan XL 5mg

180
Brand

$232.00

viewdetail

$ 1.29

Go To STORE
43.28%
When you buy 1 container of Ditropan XL 5mg for $232.00 at Canadian Pharmacy Meds compared to the max price for 180 of $409.00.
Canadian Pharmacy Meds Pharmacy is certified by
1 container (180): Ditropan XL 5mg
$232.00
Regular Shipping:
$10.00
Coupon Discount
$24.2
Total:
$217.8
Go To Store

Ditropan Prices from Online Pharmacies Canada

Ditropan 5mg

90
Brand

$116.20

viewdetail

$ 1.29

Go To STORE
54.25%
When you buy 1 container of Ditropan 5mg for $116.20 at Online Pharmacies Canada compared to the max price for 90 of $254.00.
Online Pharmacies Canada Pharmacy is certified by
1 container (90): Ditropan 5mg
$116.20
Regular Shipping:
$9.95
Total:
$126.15
Go To Store

Ditropan Prices from Online Pharmacies Canada

Ditropan XL 5mg

90
Brand

$116.20

viewdetail

$ 1.29

Go To STORE
54.25%
When you buy 1 container of Ditropan XL 5mg for $116.20 at Online Pharmacies Canada compared to the max price for 90 of $254.00.
Online Pharmacies Canada Pharmacy is certified by
1 container (90): Ditropan XL 5mg
$116.20
Regular Shipping:
$9.95
Total:
$126.15
Go To Store

Ditropan Prices from Pharma Passport

Ditropan XL 5mg

90
Brand

$116.78

viewdetail

$ 1.30

Go To STORE
54.02%
When you buy 1 container of Ditropan XL 5mg for $116.78 at Pharma Passport compared to the max price for 90 of $254.00.
1 container (90): Ditropan XL 5mg
$116.78
Regular Shipping:
$9.95
Total:
$126.73
Go To Store

Ditropan Prices from Pharma Passport

Ditropan 5mg

90
Brand

$116.78

viewdetail

$ 1.30

Go To STORE
54.02%
When you buy 1 container of Ditropan 5mg for $116.78 at Pharma Passport compared to the max price for 90 of $254.00.
1 container (90): Ditropan 5mg
$116.78
Regular Shipping:
$9.95
Total:
$126.73
Go To Store

Ditropan Prices from Canada Drug Center

Ditropan XL 5mg

90
Brand

$138.00

viewdetail

$ 1.53

Go To STORE
45.67%
When you buy 1 container of Ditropan XL 5mg for $138.00 at Canada Drug Center compared to the max price for 90 of $254.00.
Canada Drug Center Pharmacy is certified by
1 container (90): Ditropan XL 5mg
$138.00
Regular Shipping:
$9.99
Coupon Discount
$14.799
Total:
$133.191
Go To Store

Ditropan Prices from Canadian Pharmacy Meds

Ditropan XL 5mg

90
Brand

$139.00

viewdetail

$ 1.54

Go To STORE
45.28%
When you buy 1 container of Ditropan XL 5mg for $139.00 at Canadian Pharmacy Meds compared to the max price for 90 of $254.00.
Canadian Pharmacy Meds Pharmacy is certified by
1 container (90): Ditropan XL 5mg
$139.00
Regular Shipping:
$10.00
Coupon Discount
$14.9
Total:
$134.1
Go To Store

Ditropan Prices from Canada Drug Center

Ditropan XL 5mg

60
Brand

$111.00

viewdetail

$ 1.85

Go To STORE
6.72%
When you buy 1 container of Ditropan XL 5mg for $111.00 at Canada Drug Center compared to the max price for 60 of $119.00.
Canada Drug Center Pharmacy is certified by
1 container (60): Ditropan XL 5mg
$111.00
Regular Shipping:
$9.99
Coupon Discount
$12.099
Total:
$108.891
Go To Store

Ditropan Prices from Canadian Pharmacy Meds

Ditropan XL 5mg

60
Brand

$112.00

viewdetail

$ 1.87

Go To STORE
5.88%
When you buy 1 container of Ditropan XL 5mg for $112.00 at Canadian Pharmacy Meds compared to the max price for 60 of $119.00.
Canadian Pharmacy Meds Pharmacy is certified by
1 container (60): Ditropan XL 5mg
$112.00
Regular Shipping:
$10.00
Coupon Discount
$12.2
Total:
$109.8
Go To Store

Ditropan Prices from Canada Drug Center

Ditropan XL 10mg

900
Brand

$1713.00

viewdetail

$ 1.90

Go To STORE
0.06%
When you buy 1 container of Ditropan XL 10mg for $1713.00 at Canada Drug Center compared to the max price for 900 of $1714.00.
Canada Drug Center Pharmacy is certified by
1 container (900): Ditropan XL 10mg
$1713.00
Regular Shipping:
$9.99
Coupon Discount
$172.299
Total:
$1550.691
Go To Store

Ditropan Prices from Canadian Pharmacy Meds

Ditropan XL 10mg

900
Brand

$1714.00

viewdetail

$ 1.90

Go To STORE
0.00%
When you buy 1 container of Ditropan XL 10mg for $1714.00 at Canadian Pharmacy Meds compared to the max price for 900 of $1714.00.
Canadian Pharmacy Meds Pharmacy is certified by
1 container (900): Ditropan XL 10mg
$1714.00
Regular Shipping:
$10.00
Coupon Discount
$172.4
Total:
$1551.6
Go To Store

Ditropan Prices from Canada Drug Center

Ditropan XL 10mg

720
Brand

$1379.00

viewdetail

$ 1.92

Go To STORE
0.07%
When you buy 1 container of Ditropan XL 10mg for $1379.00 at Canada Drug Center compared to the max price for 720 of $1380.00.
Canada Drug Center Pharmacy is certified by
1 container (720): Ditropan XL 10mg
$1379.00
Regular Shipping:
$9.99
Coupon Discount
$138.899
Total:
$1250.091
Go To Store

Ditropan Prices from Canadian Pharmacy Meds

Ditropan XL 10mg

720
Brand

$1380.00

viewdetail

$ 1.92

Go To STORE
0.00%
When you buy 1 container of Ditropan XL 10mg for $1380.00 at Canadian Pharmacy Meds compared to the max price for 720 of $1380.00.
Canadian Pharmacy Meds Pharmacy is certified by
1 container (720): Ditropan XL 10mg
$1380.00
Regular Shipping:
$10.00
Coupon Discount
$139
Total:
$1251
Go To Store

Ditropan Prices from Canada Drug Center

Ditropan XL 10mg

180
Brand

$348.00

viewdetail

$ 1.93

Go To STORE
14.91%
When you buy 1 container of Ditropan XL 10mg for $348.00 at Canada Drug Center compared to the max price for 180 of $409.00.
Canada Drug Center Pharmacy is certified by
1 container (180): Ditropan XL 10mg
$348.00
Regular Shipping:
$9.99
Coupon Discount
$35.799
Total:
$322.191
Go To Store

Ditropan Prices from Canada Drug Center

Ditropan XL 5mg

30
Brand

$58.00

viewdetail

$ 1.93

Go To STORE
24.18%
When you buy 1 container of Ditropan XL 5mg for $58.00 at Canada Drug Center compared to the max price for 30 of $76.50.
Canada Drug Center Pharmacy is certified by
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Ditropan XL 10mg

180
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$349.00

viewdetail

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90 tablet
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90 tablet
Brand

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30
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60
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30
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90
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Ditropan XL 10mg

90 tablet
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Ditropan XL 5mg

30 tablet
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Ditropan XL 10mg

90 tablet
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Ditropan XL 5mg

30 tablet
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Ditropan XL 5mg

360
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$ 2.26

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Ditropan 10 mg

180
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Ditropan XL 5mg

360
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360
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Ditropan XL 5mg

360
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360
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Ditropan 10 mg

90
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$209.00

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Ditropan XL 5mg

90
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$211.70

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Ditropan XL 5mg

90
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Ditropan 15 mg

100
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$245.00

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Ditropan XL 10mg

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Ditropan XL 10mg

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Ditropan 10mg

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$249.30

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Ditropan xl 10mg

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Ditropan Information

Product Code
17314-9200
Company Name
Alza Corporation
Dosage From
TABLET
Strength
5 mg
Active Ingredient
oxybutynin chloride

Ditropan (Oxybutynin) Description

Each scored biconvex, engraved blue Ditropan (Oxybutynin) (oxybutynin chloride) Tablet contains 5 mg of oxybutynin chloride. Chemically, oxybutynin chloride is d,l (racemic) 4-diethylamino-2-butynyl phenylcyclohexylglycolate hydrochloride. The empirical formula of oxybutynin chloride is CHNO•HCl. The structural formula appears below:

Oxybutynin chloride is a white crystalline solid with a molecular weight of 393.9. It is readily soluble in water and acids, but relatively insoluble in alkalis.

Ditropan (Oxybutynin) Tablets also contain calcium stearate, FD&C Blue #1 Lake, lactose, and microcrystalline cellulose.

Ditropan (Oxybutynin) Tablets are for oral administration.

Therapeutic Category: Antispasmodic, anticholinergic.

Ditropan (Oxybutynin) Clinical Pharmacology

Oxybutynin chloride exerts a direct antispasmodic effect on smooth muscle and inhibits the muscarinic action of acetylcholine on smooth muscle. Oxybutynin chloride exhibits only one fifth of the anticholinergic activity of atropine on the rabbit detrusor muscle, but four to ten times the antispasmodic activity. No blocking effects occur at skeletal neuromuscular junctions or autonomic ganglia (antinicotinic effects).

Oxybutynin chloride relaxes bladder smooth muscle. In patients with conditions characterized by involuntary bladder contractions, cystometric studies have demonstrated that oxybutynin chloride increases bladder (vesical) capacity, diminishes the frequency of uninhibited contractions of the detrusor muscle, and delays the initial desire to void. Oxybutynin chloride thus decreases urgency and the frequency of both incontinent episodes and voluntary urination.

Antimuscarinic activity resides predominately in the R-isomer. A metabolite, desethyloxybutynin, has pharmacological activity similar to that of oxybutynin in studies.

Ditropan (Oxybutynin) Clinical Studies

Ditropan (Oxybutynin) was well tolerated in patients administered the drug in controlled studies of 30 days' duration and in uncontrolled studies in which some of the patients received the drug for 2 years.

Ditropan (Oxybutynin) Indications And Usage

Ditropan (Oxybutynin) (oxybutynin chloride) is indicated for the relief of symptoms of bladder instability associated with voiding in patients with uninhibited neurogenic or reflex neurogenic bladder (i.e., urgency, frequency, urinary leakage, urge incontinence, dysuria).

Ditropan (Oxybutynin) Contraindications

Ditropan (Oxybutynin) (oxybutynin chloride) is contraindicated in patients with urinary retention, gastric retention and other severe decreased gastrointestinal motility conditions, uncontrolled narrow-angle glaucoma and in patients who are at risk for these conditions.

Ditropan (Oxybutynin) is also contraindicated in patients who have demonstrated hypersensitivity to the drug substance or other components of the product.

Ditropan (Oxybutynin) Precautions

Oxybutynin is associated with anticholinergic central nervous system (CNS) effects (See ). A variety of CNS anticholinergic effects have been reported, including hallucinations, agitation, confusion and somnolence. Patients should be monitored for signs of anticholinergic CNS effects, particularly in the first few months after beginning treatment or increasing the dose. If a patient experiences anticholinergic CNS effects, dose reduction or drug discontinuation should be considered.

Ditropan (Oxybutynin) should be used with caution in patients with preexisting dementia treated with cholinesterase inhibitors due to the risk of aggravation of symptoms.

Ditropan (Oxybutynin) (oxybutynin chloride) should be used with caution in the frail elderly, in patients with hepatic or renal impairment, and in patients with myasthenia gravis.

Ditropan (Oxybutynin) may aggravate the symptoms of hyperthyroidism, coronary heart disease, congestive heart failure, cardiac arrhythmias, hiatal hernia, tachycardia, hypertension, myasthenia gravis, and prostatic hypertrophy.

Ditropan (Oxybutynin) should be administered with caution to patients with gastrointestinal obstructive disorders because of the risk of gastric retention (see).

Administration of Ditropan (Oxybutynin) to patients with ulcerative colitis may suppress intestinal motility to the point of producing a paralytic ileus and precipitate or aggravate toxic megacolon, a serious complication of the disease.

Ditropan (Oxybutynin) , like other anticholinergic drugs, may decrease gastrointestinal motility and should be used with caution in patients with conditions such as ulcerative colitis, and intestinal atony.

Ditropan (Oxybutynin) should be used with caution in patients who have gastroesophageal reflux and/or who are concurrently taking drugs (such as bisphosphonates) that can cause or exacerbate esophagitis.

Patients should be informed that heat prostration (fever and heat stroke due to decreased sweating) can occur when anticholinergics such as oxybutynin chloride are administered in the presence of high environmental temperature.

Because anticholinergic agents such as oxybutynin may produce drowsiness (somnolence), or blurred vision, patients should be advised to exercise caution.

Patients should be informed that alcohol may enhance the drowsiness caused by anticholinergic agents such as oxybutynin.

The concomitant use of oxybutynin with other anticholinergic drugs or with other agents which produce dry mouth, constipation, somnolence (drowsiness), and/or other anticholinergic-like effects may increase the frequency and/or severity of such effects.

Anticholinergic agents may potentially alter the absorption of some concomitantly administered drugs due to anticholinergic effects on gastrointestinal motility. This may be of concern for drugs with a narrow therapeutic index.

Mean oxybutynin chloride plasma concentrations were approximately 3–4 fold higher when Ditropan (Oxybutynin) was administered with ketoconazole, a potent CYP3A4 inhibitor.

Other inhibitors of the cytochrome P450 3A4 enzyme system, such as antimycotic agents (e.g., itraconazole and miconazole) or macrolide antibiotics (e.g., erythromycin and clarithromycin), may alter oxybutynin mean pharmacokinetic parameters (i.e., C and AUC). The clinical relevance of such potential interactions is not known. Caution should be used when such drugs are co-administered.

A 24-month study in rats at dosages of oxybutynin chloride of 20, 80, and 160 mg/kg/day showed no evidence of carcinogenicity. These doses are approximately 6, 25, and 50 times the maximum human exposure, based on surface area.

Oxybutynin chloride showed no increase of mutagenic activity when tested in and test systems.

Reproduction studies using oxybutynin chloride in the hamster, rabbit, rat, and mouse have shown no definite evidence of impaired fertility.

The safety and efficacy of Ditropan (Oxybutynin) administration have been demonstrated for pediatric patients 5 years of age and older (see).

The safety and efficacy of Ditropan (Oxybutynin) Tablets were studied in 30 children in a 24-week, open-label trial. Patients were aged 5–15 years, all had symptoms of detrusor overactivity in association with a neurological condition (e.g., spina bifida), all used clean intermittent catheterization, and all were current users of oxybutynin chloride. Study results demonstrated that the administration of Ditropan (Oxybutynin) was associated with improvement in clinical and urodynamic parameters.

At total daily doses ranging from 5 mg to 15 mg, treatment with Ditropan (Oxybutynin) Tablets was associated with an increase from baseline in mean urine volume per catheterization from 122 mL to 145 mL, an increase from baseline in mean urine volume after morning awakening from 148 mL to 168 mL, and an increase from baseline in the mean percentage of catheterizations without a leaking episode from 43% to 61%. Urodynamic results in these patients were consistent with the clinical results. Treatment with Ditropan (Oxybutynin) Tablets was associated with an increase from baseline in maximum cystometric capacity from 230 mL to 279 mL, a decrease from baseline in mean detrusor pressure at maximum cystometric capacity from 36 cm H0 to 33 cm H0, and a reduction in the percentage of patients demonstrating uninhibited detrusor contractions (of at least 15 cm H0) from 39% to 20%.

As there is insufficient clinical data for pediatric populations under age 5, Ditropan (Oxybutynin) is not recommended for this age group.

Ditropan (Oxybutynin) Adverse Reactions

The safety and efficacy of Ditropan (Oxybutynin) (oxybutynin chloride) was evaluated in a total of 199 patients in three clinical trials. These participants were treated with Ditropan (Oxybutynin) 5–20 mg/day for up to 6 weeks. Table 3 shows the incidence of adverse events judged by investigators to be at least possibly related to treatment and reported by at least 5% of patients.

The most common adverse events reported by patients receiving Ditropan (Oxybutynin) 5–20 mg/day were the expected side effects of anticholinergic agents. The incidence of dry mouth was dose-related.

In addition, the following adverse events were reported by 1 to

Ditropan (Oxybutynin) Overdosage

Treatment should be symptomatic and supportive. Activated charcoal as well as a cathartic may be administered.

Overdosage with oxybutynin chloride has been associated with anticholinergic effects including central nervous system excitation (e.g., restlessness, tremor, irritability, convulsions, delirium, hallucinations), flushing, fever, dehydration, cardiac arrhythmia, vomiting, and urinary retention. Other symptoms may include hypotension or hypertension, respiratory failure, paralysis, and coma.

Ingestion of 100 mg oxybutynin chloride in association with alcohol has been reported in a 13-year-old boy who experienced memory loss, and a 34 year old woman who developed stupor, followed by disorientation and agitation on awakening, dilated pupils, dry skin, cardiac arrhythmia, and retention of urine. Both patients fully recovered with symptomatic treatment.

Ditropan (Oxybutynin) Dosage And Administration

Adults: The usual dose is one 5-mg tablet two to three times a day. The maximum recommended dose is one 5-mg tablet four times a day. A lower starting dose of 2.5 mg two or three times a day is recommended for the frail elderly.

Pediatric patients over 5 years of age: The usual dose is one 5-mg tablet two times a day. The maximum recommended dose is one 5-mg tablet three times a day.

Ditropan (Oxybutynin) How Supplied

Ditropan (Oxybutynin) (oxybutynin chloride) Tablets are supplied in bottles of 100 tablets (NDC 17314-9200-1). Blue scored tablets (5 mg) are engraved with Ditropan (Oxybutynin) on one side with 92 and 00, separated by a horizontal score, on the other side.

Pharmacist: Dispense in tight, light-resistant container as defined in the USP.

Store at controlled room temperature 59–86°F (15–30°C).

Ditropan (Oxybutynin) References

Manufactured by sanofi-aventis U.S. LLC, Kansas City, MO 64137.

(OMP Logo)

633-20-616-4

Ditropan (Oxybutynin) Principal Display Panel - Tablet Bottle

NDC 17314-9200-1

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