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News on Velcade (bortezomib)

Velcade Maintenance Shows Little Improvement For Myeloma Patients Who Fail To ... - The Myeloma Beacon

Velcade Maintenance Shows Little Improvement For Myeloma Patients Who Fail To ...The Myeloma BeaconThe use of single-agent Velcade as maintenance therapy does not significantly improve the response of multiple myeloma patients who fail to achieve a ...

Itraconazole May Worsen Velcade-Induced Side Effects In Relapsed Multiple ... - The Myeloma Beacon

Itraconazole May Worsen Velcade-Induced Side Effects In Relapsed Multiple ...The Myeloma BeaconA small study in Japan showed that relapsed multiple myeloma patients treated simultaneously with Velcade and itraconazole experienced greater ...

Takeda Profit Falls While Daiichi Sankyo Sails On In 1H - Wall Street Journal

Takeda Profit Falls While Daiichi Sankyo Sails On In 1HWall Street JournalWhile strong sales of its diabetes treatment Actos and relatively new products such as Velcade for multiple myeloma made up for part of the revenue fall, ...and more��

Chinese Study Suggests That Velcade May Protect Against Blood Clots In Newly ... - The Myeloma Beacon

Chinese Study Suggests That Velcade May Protect Against Blood Clots In Newly ...The Myeloma BeaconA recent study conducted in China demonstrated that the addition of Velcade to initial thalidomide-dexamethasone treatment confers a low risk of blood clot ...

Velcade (bortezomib)

Last updated on: Jan 24, 2007

Brand Name:	Velcade
Active Ingredient:	bortezomib
Strength(s):	3.5mg/10mL vial
Dosage Form(s):	Injection
Company Name:	Millennium Pharmaceuticals
Availability:	Prescription only
*Date Approved by FDA:	May 13, 2003
*Approval by FDA does not mean that the drug is available for consumers at this time. This information is provided by the U.S. Food & Drug Administration. For more information about this drug, click here.

What is Velcade used for?

Velcade is a chemotherapy medicine (medicine used to kill cancer cells) that is used to treat a type of cancer called multiple myeloma. It should only be used in people:
- who have already been treated with one other type of chemotherapy medicine, and
- whose cancer has still progressed on the most recent therapy.
Velcade should not be the first chemotherapy medicine that is used to treat multiple myeloma.

Velcade has been shown to increase the response rate, time to disease progression, and survival for patients with myeloma who have progressed on one or more prior therapies.

Who should not be treated with Velcade?

Do not use Velcade if you are allergic to bortezomib, boron, or mannitol.

Special Warning(s) with Velcade:

Velcade may cause peripheral neuropathy, a condition that includes numbness, pain, or a burning feeling in the feet or hands.
Velcade may decrease blood pressure, causing dizziness, lightheadedness, or fainting spells.
Velcade can cause or worsen congestive heart failure in patients with heart disease or who have risk factors for heart disease.
Velcade may cause severe nausea, diarrhea, constipation, or vomiting, which may lead to dehydration (loss of body fluids).
Velcade may decrease the number of platelets in the blood, causing easier bruising and bleeding.

Call your healthcare provider right away if you get any of the above side effects.

What should I tell my doctor or healthcare provider?

Tell your healthcare provider if you:

have or had liver or kidney problems
have or had a history of heart disease
are trying to become pregnant, are already pregnant, or are breast-feeding

Tell your healthcare provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your healthcare provider if you take:

amiodarone
antiviral medicines
isoniazid
nitrofurantoin
cholesterol medicines called ?statins?
diabetes medicines
blood pressure medicines

These medicines may affect how Velcade works, or Velcade may affect how these medicines work. Some medicines may also cause the same side effects as Velcade, leading to more severe side effects.

What are some possible side effects of Velcade? (This is NOT a complete list of side effects reported with Velcade. Your healthcare provider or pharmacist can discuss with you a more complete list of side effects.)

Some common side effects with Velcade include: