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News on Temodar (temozolomide)

Celldex surges on brain cancer drug study data - BusinessWeek

Celldex surges on brain cancer drug study dataBusinessWeek... in addition to surgery, radiation treatment, and the cancer drug Temodar lived longer than patients who only received surgery, radiation, and Temodar. ...and more��

Merck Announces Third-Quarter 2010 Financial Results - MarketWatch (press release)

Merck Announces Third-Quarter 2010 Financial ResultsMarketWatch (press release)Sales of TEMODAR (temozolomide), a treatment for certain types of brain tumors, were $254 million for the third quarter of 2010. Sales of CAELYX (pegylated ...and more��

Antigenics Reports Third Quarter 2010 Financial Results - MarketWatch (press release)

Antigenics Reports Third Quarter 2010 Financial ResultsMarketWatch (press release)This trial involves the administration of Oncophage in combination with radiation and Temodar (Merck; temozolomide). Based on encouraging early results from ...and more��

Antigenics Announces Expansion of Phase 2 Trial in Glioma - MarketWatch (press release)

Antigenics Announces Expansion of Phase 2 Trial in GliomaMarketWatch (press release)According to the protocol, patients receive Temodar(R) concurrently with HSPPC-96. The trial is supported through grants from the American Brain Tumor ...and more��

Temodar (temozolomide)

Last updated on: Jan 24, 2007

Brand Name: Temodar
Active Ingredient:   temozolomide
Strength(s): 5mg, 20mg, 100mg, & 250mg
Dosage Form(s):   Capsules
Company Name:    Schering Corporation
Availability:         Prescription only
*Date Approved by FDA:   August 11, 1999
*Approval by FDA does not mean that the drug is available to consumers at this time.

This information is provided by the U.S. Food & Drug Administration.
For more information about this drug, click here.

What is Temodar used for?

Temodar is used to treat a form of brain cancer (anaplastic astrocytoma) in adults whose disease progressed after radiation therapy and chemotherapy with nitrosoureas and procarbazine, drugs commonly used to treat brain cancers.

Temodar is used to treat adults newly diagnosed with a form of brain cancer (glioblastoma multiforme) while also being treated with radiotherapy and then used as a maintenance treatment.

At this time, it is not known whether Temodar will improve symptoms, keep the disease from getting worse, or help patients live longer.

Who should not take Temodar?

You should not take Temodar if you have had an allergic reaction to dacarbazine, another drug used to treat cancer, because you may have a similar reaction while taking Temodar.

General Precautions with Temodar: 

Read the patient information that comes with Temodar before you start taking it and every time you renew your prescription in case the information has been updated.

Temodar can cause a decrease in the body's ability to produce bone marrow (myelosuppression), which is needed to form several components of the blood. Your doctor will check you for this condition while you are being treated with Temodar.

If you have a history of severe liver or kidney problems your doctor will evaluate and decide if Temodar is right for you.

Because Temodar can cause birth defects, women should avoid becoming pregnant and stop breast-feeding a baby and nursing while taking Temodar. Tell your healthcare provider if you are already pregnant or are breast-feeding. Men and women taking Temodar should use effective birth control.

Keep this medicine away from children and pets.

What should I tell my doctor or healthcare provider?

Because certain other medications can interact with Temodar, review all medications that you are taking with your healthcare provider, including those that you take without a prescription.

Because Temodar can cause birth defects, women should avoid becoming pregnant and stop breast-feeding a baby and nursing while taking Temodar. Tell your healthcare provider if you are already pregnant or are breast-feeding. Men and women taking Temodar should use effective birth control.

What are some possible side effects of Temodar? (This is NOT a complete list of side effects reported with Temodar. Your healthcare provider can discuss with you a more complete list of side effects.)  

Some possible side effects are:

Other side effects include:


This information is provided by the U.S. Food & Drug Administration.
For more information about this drug, click here.

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