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News on Sustiva (efavirenz)

Bristol-Myers Squibb Reports 3Q Results - Trading Markets (press release)

Bristol-Myers Squibb Reports 3Q ResultsTrading Markets (press release)Sales of PLAVIX rose 7 percent, BARACLUDE rose 19 percent, SUSTIVA rose 9 percent and REYATAZ rose 4 percent. Third quarter sales of Sprycel and ORENCIA ...

Switch From Efavirenz Improves Vitamin D Levels - AIDSmeds.com HIV/AIDS Treatment News

Switch From Efavirenz Improves Vitamin D LevelsAIDSmeds.com HIV/AIDS Treatment NewsPeople with vitamin D deficiency who switched off efavirenz—found in Sustiva and Atripla—were likely to see improvements in their vitamin D levels. ...

IDSA: Mild Liver Impairment Doesn't Interfere with Efavirenz - MedPage Today

IDSA: Mild Liver Impairment Doesn't Interfere with EfavirenzMedPage TodayVANCOUVER -- The pharmacokinetics of the anti-human immunodeficiency virus drug efavirenz (Sustiva) do not appear to be adversely affected when administered ...and more��

Gilead 3rd-quarter profit driven by HIV sales - Reuters

RTT NewsGilead 3rd-quarter profit driven by HIV salesReutersN) Sustiva into a single pill, rose 23 percent to $742.7 million. The totals beat analysts' estimates of $657 million for Truvada and $737 million for ...What's Your Next Trick, Gilead?Motley FoolGilead 3Q Profit Rises 4.7% On Strong HIV SalesWall Street Journalall 82 news articles��

Sustiva (efavirenz)

Last updated on: Jan 24, 2007

Brand Name:	Sustiva
Active Ingredient:	efavirenz
Strength(s):	50mg, 100mg, and 200mg Capsules, 300 mg and 600 mg Tablets
Dosage Form(s):	Capsules and Tablets
Company Name:	DuPont Pharmaceuticals Company
Availability:	Prescription only
*Dated Approved by FDA:	September 17, 1998
*Approval by FDA does not mean that the drug is available for consumers at this time. This information is provided by the U.S. Food & Drug Administration. For more information about this drug, click here.

What is Sustiva used for?

Sustiva is used in combination with other anti-HIV medications to treat HIV infection.
Sustiva is not a cure for HIV infection. You may continue to develop infections and other complications associated with HIV disease. There are no data that Sustiva can reduce the risk of transmitting HIV to others through sexual contact or blood contamination.

Special Warnings Concerning Sustiva:

Sustiva should not be taken alone to treat HIV. Because resistance to the HIV virus can occur quickly with single drug treatment, Sustiva should always be taken in combination with at least one other anti-HIV medication. If your current treatment is not working, Sustiva should not be added by itself.
Tell your health care provider if you are trying to become pregnant, are pregnant, or are breast-feeding. You should not become pregnant or breast-feed while taking Sustiva. Before starting Sustiva, women capable of having children should take a pregnancy test. While taking Sustiva you should always use a barrier form of birth control (e.g., condom, diaphragm) along with another effective method of birth control (e.g., oral birth control pill).
Find out about medicines that should NOT be taken with Sustiva. Review all medications that you are taking with your health care provider, including prescription and non-prescription medication, and herbal products. There are potential drug interactions that can cause serious side effects. You must not take Sustiva with:
- astemizole
- cisapride
- midazolam
- triazolam
- ergot derivatives
Doses of other medications may need to be adjusted.

General Precautions with Sustiva:

The long-term effects of Sustiva on HIV infection are not known at this time.
Tell your health care provider right away if you experience delusions, unusual behavior, or suddenly feel depressed.
Avoid taking Sustiva while using alcohol or drugs that affect the mind or behavior.
Sustiva may cause dizziness, problems concentrating and/or drowsiness. Therefore, do not drive or operate heavy machinery until you know how you will react to Sustiva.
Sustiva may cause a skin rash in the first or second week of treatment. The rash generally lasts less than a month. However, some patients develop a severe rash with blistering. Rash occurs more frequently in children than adults. In a small number of patients rash may be severe. If you develop a skin rash tell your health care provider.
If you have or have a history of hepatitis, or if you are taking other medications that are harmful to the liver, see your health care provider for regular monitoring.
Your health care provider may want to check your cholesterol levels regularly while you are taking Sustiva.

What are some possible side effects of Sustiva? (This is not a complete list of side effects reported with Sustiva. Your health care provider can discuss with you a more complete list of side effects.)

Tell your health care provider about any side effects you have.

If you experience dizziness, difficulty concentrating, drowsiness, unusual dreams, or trouble sleeping, tell your health care provider. These symptoms can begin during the first few days of taking Sustiva and usually go away after 2-4 weeks of treatment. Taking Sustiva at bedtime can help, and is recommended for the first few weeks of treatment

Skin rash is a common side effect of Sustiva especially in children. (See General Precautions)

Other side effects may include: