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News on Rosuvastatin Calcium (Crestor)

Patent expiries bite into AstraZeneca revenues - InPharm

Reuters UKPatent expiries bite into AstraZeneca revenuesInPharmRevenue dropped by 2% to $7.9 billion, with sales propped up by strong growth from anti-cholesterol drug Crestor, which grew 20% to $1.37 billion. ...AstraZeneca Profit Hit By Legal Charges, Generic DrugsWall Street JournalAZ profits plummet, but Crestor shinesFiercePharmaAstraZeneca profits fall but Crestor sales soar againPharma TimesAFP�-Zenopa�-Bloombergall 198 news articles��

AstraZeneca sues Watson over generic Crestor - BusinessWeek

AstraZeneca sues Watson over generic CrestorBusinessWeekWatson notified AstraZeneca last month that it would seek approval for a version of Crestor, an AstraZeneca spokeswoman said. The company responded Tuesday ...AstraZeneca sues to stop Crestor patent challengeForbesWatson sued over generic CrestorPress-EnterpriseAZ sues Watson to stop copycat Crestor; Erbitux study raises KRAS questions;FiercePharmaPR Newswire (press release)�-InPharm�-Investor's Business Dailyall 41 news articles��

Universal American Announces New Medicare Part D Benefit Making LIPITOR® and ... - PR Newswire (press release)

Universal American Announces New Medicare Part D Benefit Making LIPITOR® and ...PR Newswire (press release)By forming partnerships with Pfizer and AstraZeneca, the makers of LIPITOR and CRESTOR, Universal American members can save $230 to $300(5) on these ...and more��

AstraZeneca sues Watson Pharma over generic Crestor - pharmabiz.com

AstraZeneca sues Watson Pharma over generic Crestorpharmabiz.comWatson's rosuvastatin zinc tablets are a new salt version of AstraZeneca's Crestor tablets. Crestor is indicated, as an adjunct to diet, ...

Rosuvastatin Calcium (Crestor)

Last updated on: Jan 24, 2007

What Is Crestor?

Crestor is a medicine that lowers "bad" cholesterol and triglycerides and raises "good" cholesterol in the blood. Crestor is part of a treatment program that should also include a low-fat diet and exercise.

Who Should Not Take Crestor?

Do not take Crestor if you:

Have liver problems or have persistently high liver enzymes
Are pregnant or planning to become pregnant. Crestor may harm your unborn baby. If you get pregnant, stop Crestor and call your healthcare professional right away.
Are breast-feeding. It is not known if Crestor can pass into your milk, and if it can harm your baby. You should choose to either take Crestor or breastfeed, but not both.
Are allergic to Crestor or any of its ingredients

Crestor has not been studied in children.

What Are The Risks?

Crestor may cause rare, but serious, side effects including:

Muscle damage. Crestor can cause serious muscle damage that can lead to kidney damage. The risk of muscle damage may be increased by taking certain drugs. Crestor should be used with caution if you have kidney problems, advanced age, and hypothyroidism because you are at a greater risk of muscle damage. Tell your healthcare professional if you develop unexplained muscle pain, tenderness, or weakness while on Crestor, particularly if accompanied by malaise or fever.

Liver damage. Crestor can cause liver damage like other lipid lowering medicines. This risk may be increased when Crestor is used with certain medicines. Your healthcare professional may do blood tests to check your liver before you start taking Crestor, and while you take it. Crestor should be used with caution if you have a history of liver disease or drink substantial amounts of alcohol.
Other side effects include muscle pain, constipation, weakness, abdominal pain, and nausea

What Should I Tell My Healthcare Professional?

Before starting Crestor, tell your healthcare professional about all your medical conditions, including if you:

Are pregnant or planning to become pregnant
Are breast-feeding
Have liver problems
Have kidney problems
Drink alcohol

Are There Any Interactions With Drugs Or Foods?

Tell your healthcare professional about all the medicines you take, including prescription and over the counter drugs, and supplements. Crestor and certain medicines may interact with each other causing serious side effects. Crestor and other medicines may affect each other, causing serious side effects. Especially tell your healthcare professional if you take:

Cyclosporine (Gengraf, Neoral, Sandimmune)
Warfarin (Coumadin)
Gemfibrozil (Lopid)
Drugs that may decrease the levels or activity of your body?s own steroid hormones. These drugs include ketoconazole (Nizoral), spironolactone (Aldactone), and cimetidine (Tagamet)
Aluminum and magnesium hydroxide combination antacids (for example, Maalox)

How do I take Crestor?

You should be placed on a standard lipid-lowering diet and an exercise routine before receiving Crestor and should continue these during treatment. Crestor can be taken as a single dose at any time of day, with or without food.
The dose range for Crestor is 5 to 40 mg once daily. You should start on the lowest possible dose, and never start with 40 mg. After starting or changing your dose of Crestor, your lipid levels should be checked within 2 to 4 weeks and your dose adjusted as needed.

This information is provided by the U.S. Food & Drug Administration.
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