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News on Quetiapine (Seroquel)

No Evidence to Support Recommendation to Use Atypicals Over First-Generation ... - Medscape

No Evidence to Support Recommendation to Use Atypicals Over First-Generation ...MedscapeUsing data from the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE), the investigators compared the SGAs olanzapine, quetiapine, ...

AstraZeneca profits fall but Crestor sales soar again - Pharma Times

Reuters UKAstraZeneca profits fall but Crestor sales soar againPharma TimesOther big earners were the asthma combo Symbicort (budesonide and formoterol), which rose 19% to $660 million, and the antipsychotic Seroquel (quetiapine) ...AstraZeneca Profit Fell on Generic Rivals, Legal CostsThe FINANCIAL (blog)all 198 news articles��

Seroquel Manufacturer Sues for Patent Protection - Lawyers and Settlements

Lawyers and SettlementsSeroquel Manufacturer Sues for Patent ProtectionLawyers and Settlements... drug Seroquel has issued a lawsuit against a competitor alleging patent infringement with regard to Seroquel XR (Quetiapine fumarate) in the US market. ...

AstraZeneca sues Torrent for patent violation in US - Financial Express

AstraZeneca sues Torrent for patent violation in USFinancial Express... Torrent Pharma for allegedly infringing its patent coverage related to schizophrenia drug Seroquel XR (Quetiapine fumarate) in the US market. ...

Quetiapine (Seroquel)

Last updated on: Jan 24, 2007

What is Seroquel?

Seroquel is in a class of medications called atypical antipsychotics. Antipsychotic medicines are used to treat symptoms of schizophrenia that may include hearing voices, seeing things, or sensing things that are not there, mistaken beliefs or unusual suspiciousness.
Seroquel may be used alone or with lithium or divalproex to treat acute manic episodes in adults who have a condition called Bipolar I disorder. Bipolar disorder is a mental illness that causes extreme mood swings.

What are The Risks?

The following are the major potential risks and side effects of Seroquel therapy. However, this list is not complete.

Seroquel and other antipsychotic medications can cause serious problems such as:

A life-threatening nervous system problem called neuroleptic malignant syndrome (NMS). NMS can cause a high fever, stiff muscles, sweating, a fast or irregular heart beat, change in blood pressure, and confusion. NMS can affect your kidneys. NMS is a medical emergency. Call your healthcare professional right away if you experience these symptoms.
A movement problem called tardive dyskinesia (TD). Call your healthcare professional right away if you get muscle movements that cannot be stopped.
High blood sugar and diabetes. Patients with diabetes or who have a higher chance for diabetes should have their blood sugar checked
Other serious side effects may include low blood pressure seen as dizziness, increased heart beat and possibly fainting, cataracts, seizures, low thyroid, elevated cholesterol or triglycerides, liver problems, persistent erection, increase or decrease in body temperature, and difficulty swallowing.
The most common side effects include headache, agitation, dry mouth, constipation, pain, vomiting, upset stomach and weight gain.

What Should I Tell My Healthcare Professional?

Before you start taking Seroquel, tell your healthcare professional if you:

have or had heart problems
have or had cataracts
have a thyroid disorder
have high cholesterol or triglycerides
have or had seizures.
have or had diabetes or increased blood sugar
have or had liver disease
are trying to become pregnant, are already pregnant, or are breast-feeding.
drink alcohol

Are There Any Interactions With Drugs or Foods?

Because certain other medications can interact with Seroquel, review all medications that you are taking with your health care professional, including those that you take without a prescription.

Your healthcare professional may have to adjust your dose or watch you more closely if you take the following medications:

blood pressure medicines
levodopa and medicines called dopamine agonists
phenytoin
thioridazine
antifungal or antibiotic medicines such as ketoconazole, itraconazole, fluconazole and erythromycin
lorazepam

Avoid drinking alcohol while taking Seroquel.

Is There Anything Else I Need to Know?

Dizziness, and sometimes fainting, caused by a drop in blood pressure may happen with Seroquel, especially when you first start taking this medicine or when the dose is increased.
Seroquel may impair judgment, thinking, or motor skills. You should be careful in operating machinery, including automobiles, until you know how Seroquel affects you.
It is important to avoid overheating and dehydration while taking Seroquel. Seroquel may make it harder to lower your body temperature.

This information is provided by the U.S. Food & Drug Administration.
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