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News on Paxil (paroxetine)

Paxil and Other Popular Drugs Subject of $750 Million Settlement - DrugWatch.com

Moneycontrol.comPaxil and Other Popular Drugs Subject of $750 Million SettlementDrugWatch.comIn the case of Paxil, a popular antidepressant, the tablets were produced in a manner that caused them to spit inappropriately, resulting in the potential ...GlaxoSmithKline settles bad drug case for $750MThe Associated PressGlaxoSmithKline to pay $750m fine in fraud caseBoston GlobeGlaxo Fined $750 million over Adulterated Drug ManufacturingDice NewsBoston Herald�-U.S. News & World Report�-USA Todayall 788 news articles��

Glaxo Fine Another Win for US Attorney - The Ledger

Glaxo Fine Another Win for US AttorneyThe LedgerThe company faced charges that it made and sold adulterated drugs, including the antidepressant Paxil, to Medicaid and other government payers. ...NM to get more than $194000 in drug settlementBusinessWeekGSK Pays BigChemical & Engineering NewsGSK Settles $750 Million Lawsuits over Bad ProductsSalient NewsBizjournals.comall 34 news articles��

State to get $500K in GlaxoSmithKline settlement - StandardNet

Town HallState to get $500K in GlaxoSmithKline settlementStandardNetThe whistleblower's complaint alleged GSK knowingly manufactured, distributed and sold four products — Paxil CR, Avandamet, Kytril and Bactroban — whose ...Arkansas to Get $600000 in Settlement with Drug-maker GlaxoSmithKlineArkansas Business OnlineMichigan AG: State to get $4.7M from drug caseWashington PostAG says Ark. to get nearly $700000 from drug caseBusinessWeekall 102 news articles��

Mylan says court won't block other Paxil generics - BusinessWeek

Mylan says court won't block other Paxil genericsBusinessWeekMylan is trying to stop GlaxoSmithKline PLC of Britain and Apotex of Canada from selling version of Paxil that would compete with the version Mylan has sold ...Mylan To Appeal Court Hearing In GSK CaseBenzingaMylan to Appeal Court Decision in Generic Paroxetine Hydrochloride CR CasePR Newswire (press release)Mylan denied preliminary injunction against GSK, ApotexDrug Store Newsall 33 news articles��

Paxil (paroxetine)

Last updated on: Jan 24, 2007

What Is Paroxetine?

Paroxetine is in a class of medicines called selective serotonin reuptake inhibitors (SSRIs).

Paroxetine tablets and oral suspension are used to treat:

Depression
Panic disorder
Social anxiety disorder (SAD)
Obsessive-compulsive disorder (OCD)
Posttraumatic stress disorder (PTSD)
Generalized anxiety disorder (GAD)

Paroxetine CR is used to treat:

Depression
Panic disorder
Social anxiety disorder (SAD)
Premenstrual dysphoric disorder (PMDD)

Who Should Not Take Paroxetine?

Never take paroxetine if you are taking another drug used to treat depression, called a Monoamine Oxidase Inhibitor (MAOI), or if you have stopped taking an MAOI in the last 14 days. Taking paroxetine close in time to an MAOI can result in serious, sometimes fatal reactions including:
- High body temperature
- Coma
- Seizures (convulsions)
MAOI drugs include Nardil (phenelzine sulfate), Parnate (tranylcypromine sulfate), Marplan (isocarboxazid), and other brands.
Never take paroxetine if you are taking Mellaril (thioridazine), used to treat schizophrenia, because it can result in serious heart beat problems.

What Are The Risks?

Suicidal thoughts or actions: See FDA Alert.
Stopping paroxetine: Do not stop taking paroxetine suddenly because you could get side effects. Your healthcare professional will slowly decrease your dose.
Bleeding problems: Paroxetine may cause bleeding problems, especially if taken with aspirin, NSAIDs (nonsteroidal anti-inflammatory drugs, such as ibuprofen or naproxen), or other drugs that affect bleeding.
Mania: You may become hyperactive, excitable or elated.
Seizures: You may experience a seizure (convulsion) even if you are not taking paroxetine close in time with a MAOI.
Pregnancy: Tell your healthcare professional if you are or may be pregnant (see FDA Alert [12/2005] above). In addition to the issues discussed in the alert, babies delivered to mothers taking paroxetine late in pregnancy have developed problems, such as difficulty breathing and feeding.
Sexual problems: You may have problems with impotence (erectile dysfunction), abnormal ejaculation, difficulty reaching orgasm, or decreased libido (sexual desire).
Other side effects include weakness, dry mouth, constipation, yawning, infection, diarrhea, sweating, dizziness, tremor, nervousness, nausea, difficulty sleeping, decreased appetite, and sleepiness.
Tell your healthcare professional about all your medical conditions, especially if you have liver or kidney disease, or glaucoma. Tell your healthcare professional if you are breast-feeding or plan to breast-feed your baby.

Are There Any Interactions With Drugs or Foods?

Paroxetine may interact with medicines other than the ones already mentioned in this information sheet. These interactions can cause serious side effects. Tell your healthcare professional about all medicines, vitamins, and herbal supplements you take.
If you plan to drink alcohol, talk to your healthcare professional.