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News on Eloxatin (oxaliplatin)

Resilient Sales and Business EPS(1) in Q3 2010 - MarketWatch (press release)

Resilient Sales and Business EPS(1) in Q3 2010MarketWatch (press release)Third-quarter net sales of Eloxatin(R) reached euro 120 million (-43.5%). Following the settlement of the US patent infringement suits related to certain ...and more��

Hospira profits tumble over lost cancer drug sales - Chicago Breaking Business - Tribune

RTT NewsHospira profits tumble over lost cancer drug salesChicago Breaking Business - TribuneA settlement of patent litigation with Sanofi-Aventis, the maker of the brand drug known as Eloxatin, is keeping Hospira's generic version known as ...Hospira quarterly earnings top analysts' viewsReutersHospira posts higher profit, trims sales outlookReutersall 43 news articles��

Solid results for Sanofi, not inclined to raise Genzyme bid - Pharma Times

Moneycontrol.comSolid results for Sanofi, not inclined to raise Genzyme bidPharma TimesThe figures were also hurt by the workdown of generics inventory in the USA for colorectal cancer drug Eloxatin (oxaliplatin) which sank 43.5 % to 120 ...Sanofi chief unswayed by Genzyme forecastsFiercePharmaEmerging Markets Favor Sanofi's Q3; Raises Full-year View - UpdateRTT NewsSanofi sticks to Genzyme offer as raises FY goalMoneycontrol.comSan Francisco Chronicleall 212 news articles��

AmerisourceBergen profit view lifted at Credit Suisse - International Business Times

AmerisourceBergen profit view lifted at Credit SuisseInternational Business TimesWe believe the combination of generic Eloxatin, Gemzar and Taxotere will potentially contribute more than the 22 cents we estimated Eloxatin contributed in ...

Eloxatin (oxaliplatin)

Last updated on: Jan 24, 2007

What is Eloxatin, and how does it work?

Eloxatin is a platinum-based anticancer drug. It is the platinum that destroys the cancer cells. The active ingredient in Eloxatin is oxaliplatin.

What is Eloxatin used for?

Eloxatin is given in combination with 5-fluorouracil plus leucovorin (5FU/LV) to treat advanced cancer of the colon or rectum (colorectal cancer).

Is Eloxatin a cure for colorectal cancer?

At this time, it is not known whether Eloxatin will improve symptoms of colorectal cancer or help patients live longer. In clinical trials, patients treated with a combination drug regimen of Eloxatin and 5-FU/LV had a longer time before tumor progression and a higher rate of tumor shrinkage.

Who should take Eloxatin?

Eloxatin is currently approved for patients whose cancer has recurred (come back) or advanced following therapy with a combination of 5-FU/LV and irinotecan. Eloxatin is not for patients with newly diagnosed colorectal cancer.

Who should not take Eloxatin?

Eloxatin should not be given to patients with an allergy to platinum compounds. Some signs of an allergic reaction include: rash, hives, swelling of the lips and tongue, and difficulty breathing.
Eloxatin should not be given to pregnant women or women who are trying to become pregnant, because Eloxatin may cause harm to an unborn child. Women should avoid becoming pregnant while being treated with Eloxatin.

Eloxatin is not for patients with newly diagnosed colorectal cancer.

How is Eloxatin given?

Eloxatin is a clear liquid that is given though a drip into a vein.

What are the side effects of Eloxatin?

Eloxatin can cause numbness or tingling in the fingers and toes and around the mouth or throat. This side effect is usually worse if the patient is cold or around cold objects. It can happen a few hours or a few days after treatment. Sometimes the tingling or numbing may not happen with the first treatment but after several treatments. This is known as a cumulative effect and should gradually improve after treatment ends.

Eloxatin can cause a temporary drop in bone marrow function. This can cause

a drop in white blood cells, increasing the risk of infection
a drop in red blood cells (anemia), causing tiredness or shortness of breath
a drop in platelets that results in bruising or bleeding

Patients should contact their doctor if they have:

difficulty in swallowing
breathing problems
vomiting or diarrhea lasting more than 24 hours
signs of losing much fluid (dehydration) such as:
- decreased urination, dizziness or light-headedness
- dry mouth
- increased thirst
signs of infection such as:
- redness and swelling at injection site
- fever, sore throat, shivering
- pain when urinating