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News on Campath (alemtuzumab)

Is 'Free' The Best Price for Genzyme's Campath in Cancer? - Wall Street Journal (blog)

Is 'Free' The Best Price for Genzyme's Campath in Cancer?Wall Street Journal (blog)But Genzyme is considering an unusual move: giving away Campath to people with a rare blood cancer in order to charge a higher price for its use in multiple ...Genzyme May Give Away Cancer Drug To Get Higher Price In MSWall Street Journalall 4 news articles��

Genzyme Isn't Interested In Campath Discussion With Sanofi - Wall Street Journal

Moneycontrol.comGenzyme Isn't Interested In Campath Discussion With SanofiWall Street JournalThe drug is already sold as Campath to treat a type of blood cancer, but late-stage data in MS is expected to be available in mid-2011. ...Sanofi sticks to Genzyme offer and raises FY forecastReutersTrying To Break The Genzyme ImpasseWBURall 212 news articles��

Genzyme MS Drug Effective After Five Years - Wall Street Journal

The Star-Ledger - NJ.comGenzyme MS Drug Effective After Five YearsWall Street JournalThe data show that alemtuzumab, which is already sold as Campath to treat a type of blood cancer, continued to be highly effective four years after most ...Buyout Value Debate Goes on Despite 5-Year Campath DataBioWorld OnlineGenzyme sees signs of remission in 5-year MS drug dataFierceBiotechGenzyme MS drug data remains strong after 5 yearsReutersBusinessWeek�-Financial Postall 90 news articles��

AstraZeneca Starts Mid-Stage Trial Of CytoFab - Wall Street Journal

AstraZeneca Starts Mid-Stage Trial Of CytoFabWall Street JournalThat compares with a royalty of 3% on sales of Campath, a blockbuster drug for a type of blood cancer sold by Genzyme Corp. (GENZ) that has become a key ...and more��

Campath (alemtuzumab)

Last updated on: Jan 24, 2007

This information is provided by the U.S. Food & Drug Administration.
For more information about this drug, click here.

What Is Campath?

Campath is a type of medicine called a monoclonal antibody. It is used to treat B-cell chronic lymphocytic leukemia (B-CLL) in patients who have failed treatment with certain other cancer medicines. It is not known if Campath improves symptoms in patients with B-CLL or if it helps them live longer.

Campath is not approved to treat Multiple Sclerosis.

Who Should Not Be Treated With Campath?

You should not be given Campath if you have any of the following conditions:

an infection in your body
an immune system problem such as being HIV positive
ever had a serious allergic reaction to Campath

What Are The Risks?

The following are the major potential risks and side effects of Campath therapy. However, this list is not complete.

Infusion-related side effects. Campath is given in a vein through a tube. This is called an I.V. infusion. An I.V. infusion of Campath may cause side effects such as low blood pressure, shaking, fever, shortness of breath, chills, and rash. Your healthcare professional may give you medicine before Campath to lower the chance of these side effects.

Immunosuppression and Infections. Campath may weaken your immune system, making it easier for you to get infections. Your healthcare professional may give you medicine to reduce the chance of infection.

Bone Marrow Effects. Campath may lower the ability of the bone marrow to make blood cells. Some of these effects can be severe and lead to death.

Some common side effects that may occur with Campath treatment include:
- shaking
- fever
- low blood cell counts
- nausea
- vomiting
- rash
- tiredness
- low blood pressure
- itching

What Should I Tell My Healthcare Professional?

Before you start taking Campath, tell your healthcare professional about all of your medical conditions, including if you:

have any infections
are HIV positive
are pregnant. Women should not get pregnant during treatment with Campath. Women and men should use effective birth control during treatment with Campath and for 6 months after stopping treatment.
are breast-feeding. Women should not breastfeed during treatment with Campath and for 3 months after stopping treatment.

Can Other Medicines Or Food Affect Campath?

It is not known if Campath and other medicines can interact with each other. Tell your healthcare professional about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements. Know the medicines you take. Keep a list of them with you to show your healthcare professional.

This information is provided by the U.S. Food & Drug Administration.
For more information about this drug, click here.