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Seromycin Price Comparison

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Seromycin Prices from Canada Drugs

Seromycin 250mg

100 capsule
Generic

$703.01

viewdetail

$ 7.03

Go To STORE
0.00%
When you buy 1 container of Seromycin 250mg for $703.01 at Canada Drugs compared to the max price for 100 capsule of $703.01.
Canada Drugs Pharmacy is certified by
1 container (100 capsule): Seromycin 250mg
$703.01
Regular Shipping:
$0.00
Coupon Discount
$175.7525
Total:
$527.2575
Go To Store

Seromycin Prices from JanDrugs

Seromycin 250mg

100 capsule
Generic

$703.01

viewdetail

$ 7.03

Go To STORE
0.00%
When you buy 1 container of Seromycin 250mg for $703.01 at JanDrugs compared to the max price for 100 capsule of $703.01.
JanDrugs Pharmacy is certified by
1 container (100 capsule): Seromycin 250mg
$703.01
Regular Shipping:
$0.00
Coupon Discount
$70.301
Total:
$632.709
Go To Store

Seromycin Information

Product Code
0002-0604
Company Name
Eli Lilly and Company
Dosage From
CAPSULE
Strength
250 mg
Inactive Ingredient
D&C Yellow No. 10,FD&C Blue No. 1,FD&C Red No. 3,FD&C Yellow No. 6,Gelatin,Iron oxide,Talc,Titanium dioxide,

Seromycin (Cycloserine) Description

Seromycin (Cycloserine) (Cycloserine Capsules, USP), 3-isoxazolidinone, 4-amino–, (R)– is a broad–spectrum antibiotic that is produced by a strain of and has also been synthesized. Cycloserine is a white to off–white powder that is soluble in water and stable in alkaline solution. It is rapidly destroyed at a neutral or acid pH.

Cycloserine has a pH between 5.5 and 6.5 in a solution containing 100 mg/mL. The molecular weight of cycloserine is 102.09, and it has an empirical formula of CHNO. The structural formula of cycloserine is as follows:

Seromycin (Cycloserine) Indications And Usage

Seromycin (Cycloserine) is indicated in the treatment of active pulmonary and extrapulmonary tuberculosis (including renal disease) when the causative organisms are susceptible to this drug and when treatment with the primary medications (streptomycin, isoniazid, rifampin, and ethambutol) has proved inadequate. Like all antituberculosis drugs, Seromycin (Cycloserine) should be administered in conjunction with other effective chemotherapy and not as the sole therapeutic agent.

Seromycin (Cycloserine) may be effective in the treatment of acute urinary tract infections caused by susceptible strains of gram–positive and gram–negative bacteria, especially  spp. and . It is generally no more and is usually less effective than other antimicrobial agents in the treatment of urinary tract infections caused by bacteria other than mycobacteria. Use of Seromycin (Cycloserine) in these infections should be considered only when more conventional therapy has failed and when the organism has been demonstrated to be susceptible to the drug.

Seromycin (Cycloserine) Contraindications

Administration is contraindicated in patients with any of the following:

Seromycin (Cycloserine) Adverse Reactions

Most adverse reactions occurring during therapy with Seromycin (Cycloserine) involve the nervous system or are manifestations of drug hypersensitivity. The following side effects have been observed in patients receiving Seromycin:

Seromycin (Cycloserine) Overdosage

Acute toxicity from cycloserine can occur if more than 1 g is ingested by an adult. Chronic toxicity from cycloserine is dose related and can occur if more than 500 mg is administered daily. Patients with renal impairment will accumulate cycloserine and may develop toxicity if the dosing regimen is not modified. Patients with severe renal impairment should not receive the drug. The central nervous system is the most common organ system involved with toxicity. Toxic effects may include headache, vertigo, confusion, drowsiness, hyperirritability, paresthesias, dysarthria, and psychosis. Following larger ingestions, paresis, convulsions, and coma often occur. Ethyl alcohol may increase the risk of seizures in patients receiving cycloserine.

The oral median lethal dose in mice is 5290 mg/kg.

To obtain up–to–date information about the treatment of overdose, a good resource is your certified Regional Poison Control Center. Telephone numbers of certified poison control centers are listed in the . In managing overdosage, consider the possibility of multiple drug overdoses, interaction among drugs, and unusual drug kinetics in your patient.

Overdoses of cycloserine have been reported rarely. The following is provided to serve as a guide should such an overdose be encountered.

Protect the patient’s airway and support ventilation and perfusion. Meticulously monitor and maintain, within acceptable limits, the patient’s vital signs, blood gases, serum electrolytes, etc. Absorption of drugs from the gastrointestinal tract may be decreased by giving activated charcoal, which, in many cases, is more effective than emesis or lavage; consider charcoal instead of or in addition to gastric emptying. Repeated doses of charcoal over time may hasten elimination of some drugs that have been absorbed. Safeguard the patient’s airway when employing gastric emptying or charcoal.

In adults, many of the neurotoxic effects of cycloserine can be both treated and prevented with the administration of 200 to 300 mg of pyridoxine daily.

The use of hemodialysis has been shown to remove cycloserine from the bloodstream. This procedure should be reserved for patients with life-threatening toxicity that is unresponsive to less invasive therapy.

Seromycin (Cycloserine) Dosage And Administration

Seromycin (Cycloserine) is effective orally and is currently administered only by this route. The usual dosage is 500 mg to 1 g daily in divided doses monitored by blood levels. The initial adult dosage most frequently given is 250 mg twice daily at 12–hour intervals for the first 2 weeks. A daily dosage of 1 g should not be exceeded.

Seromycin (Cycloserine) How Supplied

Seromycin (Cycloserine) is available as a 250 mg capsule with an opaque red cap and opaque gray body imprinted with “Lilly” and “F04” in edible black ink on both the cap and the body.

   Bottles of 40 (No.12) NDC 0002-0604-40

Seromycin (Cycloserine)

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